Observational studyAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2023
Validation of a prediction system for risk of kidney allograft failure in pediatric kidney transplant recipients: An international observational study.
Observational study in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Pediatric Kidney Transplantation: A Systematic Review.Children (Basel, Switzerland) · 2026Review
- One-year creatinine predicts long-term graft survival in pediatric kidney transplant recipients.Pediatric nephrology (Berlin, Germany) · 2026Article
- Transforming nephrology through artificial intelligence: a state-of-the-art roadmap for clinical integration.Clinical kidney journal · 2026Review
- Unboxing iBox: A Critical Appraisal of Its Measurement Properties for Predicting Kidney Allograft Failure.Kidney medicine · 2026Review
- Qualified prediction system for allograft failure in real world settings: extended validation study.BMJ medicine · 2026Article
- International validation of a pre-transplant risk assessment tool for graft survival in pediatric kidney transplant recipients.Clinical kidney journal · 2025Article
- Incidence, risk factors, management strategies, and outcomes of antibody-mediated rejection in pediatric kidney transplant recipients-a multicenter analysis of the Cooperative European Paediatric Renal Transplant Initiative (CERTAIN).Pediatric nephrology (Berlin, Germany) · 2025Article
- Article
- Proceedings of the 2024 Transplant AI Symposium.Frontiers in transplantation · 2024Article
Corrections and comments
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Authors and funding
20 authors at 12 institutions in 3 countries.
Funding
Abstract
Predicting long-term kidney allograft failure is an unmet need for clinical care and clinical trial optimization in children. We aimed to validate a kidney allograft failure risk prediction system in a large international cohort of pediatric kidney transplant recipients. Patients from 20 centers in Europe and the United States, transplanted between 2004 and 2017, were included. Allograft assessment included estimated glomerular filtration rate, urine protein-to-creatinine ratio, circulating antihuman leukocyte antigen donor-specific antibody, and kidney allograft histology. Individual predictions of allograft failure were calculated using the integrative box (iBox) system. Prediction performances were assessed using discrimination and calibration. The allograft evaluations were performed in 706 kidney transplant recipients at a median time of 9.1 (interquartile range, 3.3-19.2) months posttransplant; mean estimated glomerular filtration rate was 68.7 ± 28.1 mL/min/1.73 m
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