Evidence map›Paper›PMID 37453439›Full record

SynthesisThe lancet. HIV2023

Trends in HIV testing, the treatment cascade, and HIV incidence among men who have sex with men in Africa: a systematic review and meta-analysis.

James Stannah, Nirali Soni, Jin Keng Stephen Lam, Katia Giguère, Kate M Mitchell, Nadine Kronfli, Joseph Larmarange, Raoul Moh, Marcellin Nouaman, Gérard Menan Kouamé and 2 more

Erratum issuedOpen access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The lancet. HIV, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 47 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 7 pooled it
12.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 7 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Article
  15. Article
  16. Behavioral and structural drivers of HIV in men who have sex with men in Belize: a mixed-methods study.Revista panamericana de salud publica = Pan American journal of public health · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

James StannahSchool of Population and Global Health, McGill University, Montréal, QC, Canada.
Nirali SoniMedical Research Council Centre for Global Infectious Disease Analysis, Imperial College London, London, UK.
Jin Keng Stephen LamMedical Research Council Centre for Global Infectious Disease Analysis, Imperial College London, London, UK.
Katia GiguèreInstitut national de santé publique du Québec, Québec, QC, Canada.
Kate M MitchellMedical Research Council Centre for Global Infectious Disease Analysis, Imperial College London, London, UK.
Nadine KronfliDepartment of Medicine, Division of Infectious Diseases and Chronic Viral Illness Service, McGill University Health Centre, Montréal, QC, Canada; Centre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, McGill University Health Centre, Montréal, QC, Canada.
Joseph LarmarangeCentre Population et Développement, Université Paris Cité, Institut de Recherche pour le Développement, Inserm, Paris, France.
Raoul MohPedagogical Unit of Dermatology and Infectiology, RTU Medical Science, Abidjan, Côte d'Ivoire; Programme PAC-CI, CHU de Treichville, Site ANRS, Abidjan, Côte d'Ivoire.
Marcellin NouamanProgramme PAC-CI, CHU de Treichville, Site ANRS, Abidjan, Côte d'Ivoire.
Gérard Menan KouaméProgramme PAC-CI, CHU de Treichville, Site ANRS, Abidjan, Côte d'Ivoire.
Marie-Claude BoilyMedical Research Council Centre for Global Infectious Disease Analysis, Imperial College London, London, UK. Electronic address: mc.boily@ic.ac.uk.
Mathieu Maheu-GirouxSchool of Population and Global Health, McGill University, Montréal, QC, Canada.
Imperial College London · GBMcGill University · CAProgramme PAC-CI · CIInstitut de Recherche pour le Développement · FRInstitut National de Santé Publique du Québec · CAUniversity Hospital Medical Center at Treichville · CI

Funding

SDMC: HPTN 084 Pregnancy SupplementUM1AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Elizabeth Renata Brown, Deborah J Donnell · 2011 to 2026
$204.9M
Medical Research Council MR/R015600/1NIAID NIH HHS UM1 AI068617
6 · The paper itself

Abstract

backgroundGay, bisexual, and other men who have sex with men (MSM) are disproportionately affected by HIV. In Africa, MSM face structural barriers to HIV prevention and treatment that increase their vulnerability to HIV acquisition and transmission, and undermine the HIV response. In this systematic review, we aimed to explore progress towards increases in HIV testing, improving engagement in the HIV treatment cascade, and HIV incidence reductions among MSM in Africa.

methodsWe searched Embase, MEDLINE, Global Health, Scopus, and Web of Science for cross-sectional and longitudinal studies reporting HIV testing, knowledge of status, care, antiretroviral therapy (ART) use, viral suppression, and HIV incidence among MSM in Africa published between Jan 1, 1980, and March 3, 2023. We pooled surveys using Bayesian generalised linear mixed-effects models, used meta-regression to assess time trends, and compared HIV incidence estimates among MSM with those of all men.

findingsOf 9278 articles identified, we included 152 unique studies published in 2005-23. In 2020, we estimate that 73% (95% credible interval [CrI] 62-87) of MSM had ever tested for HIV. HIV testing in the past 12 months increased over time in central, western, eastern, and southern Africa (odds ratio per year [OR

interpretationHIV incidence remains high, and might not be decreasing among MSM in Africa over time, despite some increases in HIV testing and ART use. Achieving the UNAIDS 95-95-95 targets for diagnosis, treatment, and viral suppression equitably for all requires renewed focus on this key population. Combination interventions for MSM are urgently required to reduce disparities in HIV incidence and tackle the social, structural, and behavioural factors that make MSM vulnerable to HIV acquisition.

fundingUS National Institutes of Health, UK Medical Research Council, Canadian Institutes of Health Research, and Fonds de Recherche du Québec-Santé. TRANSLATION: For the French translation of the abstract see Supplementary Materials section.

Indexed as

HIV InfectionsSexual and Gender MinoritiesAfrica, SouthernBayes TheoremCanadaCross-Sectional StudiesHIV TestingHomosexuality, MaleHumansIncidenceMale

Identifiers

PMID37453439
PMCPMC11403132
OpenAlexW4384008992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.