Evidence map›Paper›PMID 37452999›Full record

ArticleEuropean geriatric medicine2023

European position paper on polypharmacy and fall-risk-increasing drugs recommendations in the World Guidelines for Falls Prevention and Management: implications and implementation.

Nathalie van der Velde, Lotta J Seppala, Sirpa Hartikainen, Nellie Kamkar, Louise Mallet, Tahir Masud, Manuel Montero-Odasso, Eveline P van Poelgeest, Katja Thomsen, Jesper Ryg and 2 more

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in European geriatric medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Interventions for preventing falls in older people in care facilities.The Cochrane database of systematic reviews · 2025
    Pooled it
  4. Pooled it
  5. Review
  6. Article
  7. Article
  8. Article
  9. Falls in older patients treated for cancer in French outpatient departments: screening and prevention-a prospective observational study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. [Functional assessment and medication in older adults].Innere Medizin (Heidelberg, Germany) · 2026
    Article
  15. Article
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 6 countries.

Nathalie van der Velde *Amsterdam UMC, Department of Internal Medicine, Section of Geriatric Medicine, University of Amsterdam, Amsterdam, The Netherlands. n.vandervelde@amsterdamumc.nl.ORCID 0000-0002-6477-6209
Lotta J Seppala *Amsterdam UMC, Department of Internal Medicine, Section of Geriatric Medicine, University of Amsterdam, Amsterdam, The Netherlands.
Sirpa HartikainenSchool of Pharmacy, University of Eastern Finland, Kuopio, Finland.
Nellie KamkarGait and Brain Laboratory, Lawson Research Health Institute, Parkwood Hospital, London, ON, Canada.
Louise MalletFaculty of Pharmacy, University of Montreal, Montréal, Québec, Canada.
Tahir MasudNottingham University Hospitals NHS Trust, Nottingham, UK.
Manuel Montero-OdassoGait and Brain Laboratory, Lawson Research Health Institute, Parkwood Hospital, London, ON, Canada.
Eveline P van PoelgeestAmsterdam UMC, Department of Internal Medicine, Section of Geriatric Medicine, University of Amsterdam, Amsterdam, The Netherlands.
Katja ThomsenDepartment of Geriatric Medicine, Odense University Hospital, Odense, Denmark.
Jesper RygDepartment of Geriatric Medicine, Odense University Hospital, Odense, Denmark.
Mirko PetrovicDepartment of Internal Medicine and Paediatrics, Section of Geriatrics, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
EuGMS Task, Finish Group on Fall-risk-increasing drugs
Amsterdam University Medical Centers · NLUniversity of Southern Denmark · DKWestern University · CAAmsterdam Neuroscience · NLGhent University · BEMcGill University Health Centre · CANottingham University Hospitals NHS Trust · GBUniversity of Eastern Finland · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Falls prevention and management in older adults is a critical global challenge. One of the key risk factors for falls is the use of certain medications. Therefore, to prevent medication-related falls, the following is recommended in the recent World Guidelines for Falls Prevention and Management: (1) assess for fall history and the risk of falls before prescribing potential fall-risk-increasing drugs (FRIDs), (2) use a validated, structured screening and assessment tool to identify FRIDs when performing a medication review, (3) include medication review and appropriate deprescribing of FRIDs as a part of the multifactorial falls prevention intervention, and (4) in long-term care residents, if multifactorial intervention cannot be conducted due to limited resources, the falls prevention strategy should still always include deprescribing of FRIDs.In the present statement paper, the working group on medication-related falls of the World Guidelines for Falls Prevention and Management, in collaboration with the European Geriatric Medicine Society (EuGMS) Task and Finish group on FRIDs, outlines its position on how to implement and execute these recommendations in clinical practice.Preferably, the medication review should be conducted as part of a comprehensive geriatric assessment to produce a personalized and patient-centered assessment. Furthermore, the major pitfall of the published intervention studies so far is the suboptimal implementation of medication review and deprescribing. For the future, it is important to focus on gaining which elements determine successful implementation and apply the concepts of implementation science to decrease the gap between research and practice.

Indexed as

GeriatricsPolypharmacyAccidental FallsAgedHumansLong-Term CareRisk FactorsAdverse drug reactionsDeprescribingFall-risk-increasing drugsFalls preventionImplementationMedication reviewPolypharmacy

Identifiers

PMID37452999
PMCPMC10447263
OpenAlexW4384407541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.