Evidence map›Paper›PMID 37452929›Full record

ArticleDermatology and therapy2023

Treatment Preferences in Young Adults with Moderate to Severe Psoriasis: A Qualitative Study from the Nordic Countries.

Flora Nicol Balieva, Louise Catton, Birgitta W Claréus, Kjersti Danielsen, Frederik Fierens, Lars Iversen, Leena Koulu, Amra Osmanecevic, Rafael Pasternack, Lone Skov

Open access · goldAbstract read
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In one paragraph

Article in Dermatology and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 5 countries.

Flora Nicol BalievaDepartment of Dermatology, Stavanger University Hospital, Cort Adelersgate 12, Pb. 8100, 4068, Stavanger, Norway. florabalieva@gmail.com.
Louise CattonUCB Pharma, Brussels, Belgium.
Birgitta W ClaréusPsoriasis Association Treatment Wards, Stockholm, Sweden.
Kjersti DanielsenDepartment of Community Medicine, UiT, The Arctic University of Norway, Tromsø, Norway.
Frederik FierensUCB Pharma, Brussels, Belgium.
Lars IversenDepartment of Dermatology, Aarhus University Hospital, Aarhus, Denmark.
Leena KouluDepartment of Dermatology, Turku University Hospital and University of Turku, Turku, Finland.
Amra OsmanecevicDepartment of Dermatology and Venereology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Rafael PasternackDepartment of Dermatology, Tampere University Hospital, Tampere, Finland.
Lone SkovDepartment of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
UCB Pharma (Belgium) · BEAarhus University Hospital · DKTampere University Hospital · FIUiT The Arctic University of Norway · NOUniversity of Copenhagen · DKUniversity of Gothenburg · SEUniversity of Stavanger · NOUniversity of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe purpose of this study is to explore treatment preferences and identify patient characteristics in young bio-naive adults with moderate to severe psoriasis in the Nordic countries (Norway, Finland, Sweden, and Denmark).

methodsPatients were 18-45 years old and bio-naive but referred for biologic treatment of moderate to severe psoriasis. Patients were included at eight Nordic dermatology clinics. Patients with significant comorbidity or psoriatic arthritis were excluded. The Psoriasis Area and Severity Index (PASI) and Dermatology Life Quality Index (DLQI) were assessed along with basic patient information. A semistructured interview guide was used in individual qualitative interviews, asking patients about their treatment preferences and reasons, disease journey, and disease management. The interviews were analyzed using thematic content analysis. Twenty-four patients sufficed to reach saturation in this qualitative study.

resultsThe patient sample characteristics represented a qualitative variation in age, sex, symptoms, duration of disease, and country. We included a total of 12 male and 12 female patients. The mean age was 34 years (range 18-45 years), the mean age at diagnosis was 20 years (range 6-34 years), the mean ± standard deviation (SD) time since diagnosis was 13 ± 8 years, PASI was 9.5 ± 4.7, and DLQI was 15.2 ± 6.4. Interviews suggested that both the burden of disease as well as the burden of treatment influenced patient preferences regarding treatment attributes, hence getting alleviation from symptoms did not alone influence patient preferences. Time, effort, and inconvenience related to psoriasis treatments also influenced patient preferences.

conclusionsThis first in-depth, qualitative study in young bio-naive adults with psoriasis suggests that patient preferences are focusing not only on symptom relief but also on alleviating the burden of psoriasis treatment. Understanding the reasons for patient preferences and the perspectives of young adults is needed to guide individual shared decision-making in psoriasis management.

Indexed as

Disease burdenPatient preferenceSemistructured interviewsTreatment attributesTreatment burden

Identifiers

PMID37452929
PMCPMC10366034
OpenAlexW4384406233

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.