Evidence map›Paper›PMID 37452904›Full record

ArticleActa neurochirurgica2023

Incidence and presentation of vestibular schwannoma: a 3-year cohort registry study.

Rocio Fernández-Méndez, Yizhou Wan, Patrick Axon, Alexis Joannides

Open access · hybridAbstract read
In one paragraph

Article in Acta neurochirurgica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. No surgery, but headache exists? Quality of life with vestibular schwannoma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  3. Observational
  4. Vestibular Schwannomas in Pregnancy: A Case Series.Journal of neurological surgery. Part B, Skull base · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Price Transparency in the Management of Skull Base Tumors-The Price to Operate.Journal of neurological surgery. Part B, Skull base · 2025
    Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Incidence of vestibular schwannoma in Finland, 1990-2017.Acta oncologica (Stockholm, Sweden) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rocio Fernández-MéndezClinical Neurosciences, University of Cambridge, Addenbrooke's Biomedical Campus, Cambridge, Cambridgshire, CB2 0QQ, UK.
Yizhou WanClinical Neurosciences, University of Cambridge, Addenbrooke's Biomedical Campus, Cambridge, Cambridgshire, CB2 0QQ, UK. yw435@cam.ac.uk.ORCID http://orcid.org/0000-0002-3166-8711
Patrick AxonClinical Neurosciences, University of Cambridge, Addenbrooke's Biomedical Campus, Cambridge, Cambridgshire, CB2 0QQ, UK.
Alexis JoannidesClinical Neurosciences, University of Cambridge, Addenbrooke's Biomedical Campus, Cambridge, Cambridgshire, CB2 0QQ, UK.
University of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVestibular schwannoma (VS) is the most common benign tumour arising in the lateral skull base. Reported incidence rates of VS vary across geographical locations and over time. There is scarce updated evidence over the past decade on the epidemiology and mode of presentation of VS.

objectiveTo describe the epidemiology and mode of presentation of VS in the East of England between 2013 and 2016.

methodsA retrospective epidemiological analysis of data from a national VS registry and electronic patient records was conducted, including all newly diagnosed adult patients in a UK tertiary referral centre, between April 1st, 2013, and March 31st, 2016.

resultsThere were 391 new cases identified resulting in an overall mean incidence of 2.2 VS cases per 100,000 person-year. The incidence rate for all patients in the <40 age group ranged between 0.3 and 0.7 per 100,000 person-year, increasing to a range of 5.7 to 6.1 per 100,000 person-year in the 60-69 age group. The top three combinations of symptoms on presentation per patient were hearing loss and tinnitus (97, 24.8%), hearing loss alone (79, 20.2%) and hearing loss, tinnitus, and balance symptoms (61, 15.6%). The median duration of symptoms was 12 months, with a wide range from 1.4 to 300 months. Age was negatively correlated with tumour size (r = -0.14 [-0.24 to -0.04], p=0.01) and positively correlated with symptom duration (r = 0.16 [0.03-0.29], p=0.02).

conclusionsThe incidence of vestibular schwannoma has increased compared to previous studies in the UK and is similar to incidence rates reported in other countries during the past decade. It peaks in the seventh decade of life, mainly because of an increase in the diagnosis of small tumours with a long duration of audio-vestibular symptoms in older patients, compared to earlier studies.

Indexed as

Hearing LossNeuroma, AcousticTinnitusAdultAgedCohort StudiesHumansIncidenceRegistriesRetrospective StudiesAcoustic neuromaClinical registryEpidemiology studyVestibular schwannoma

Identifiers

PMID37452904
PMCPMC10542718
OpenAlexW4384407159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.