Evidence map›Paper›PMID 37452553›Full record

SynthesisNursing open2023

Adverse effects of dorsogluteal intramuscular injection versus ventrogluteal intramuscular injection: A systematic review and meta-analysis.

María Teresa Roldán-Chicano, Javier Rodríguez-Tello, Raquel Cebrián-López, James Richard Moore, María Del Mar García-López

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nursing open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06834113 (Impact of Two Types of Interventions), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06834113 narecruitingnot on this mapstarted 2025, after this paper: background citation

Impact of Two Types of Interventions (Ventrogluteal Versus Dorsogluteal Injection Site; Virtual Reality Headset: Presence or Absence) on Pain After Injections of Vocabria® (Cabotegravir) and Rekambys® (Rilpivirine) in Patients Infected With Human Immunodeficiency Virus -1

TypeinterventionalSponsorCentre Hospitalier Régional d'OrléansRan2025 to 2026Enrolled120ConditionsHIV I Infection, Injection PainArmsDorsogluteal intramuscular injection
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Tailoring biomaterials for vaccine delivery.Journal of nanobiotechnology · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

María Teresa Roldán-ChicanoSanta Lucia, University General Hospital, Murcia Health Service, Cartagena, Spain.ORCID 0000-0002-8619-4816
Javier Rodríguez-TelloSanta Lucia, University General Hospital, Murcia Health Service, Cartagena, Spain.ORCID 0000-0001-7673-1019
Raquel Cebrián-LópezSanta Lucia, University General Hospital, Murcia Health Service, Cartagena, Spain.ORCID 0000-0001-9286-4858
James Richard MooreMurcia Health Service, Cartagena, Spain.ORCID 0000-0001-9284-8540
María Del Mar García-LópezIsaac Peral Health Center, Cartagena, Murcia Health Service, Cartagena, Spain.ORCID 0000-0003-0522-7936
Universidad Politécnica de Cartagena · ESSanta Lucía University General Hospital · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo determine adverse effects of ventrogluteal intramuscular injections versus dorsogluteal intramuscular injections.

designA systematic review and meta-analysis.

methodsMEDLINE, EMBASE, CINHAL, CENTRAL, LILACS(BVS), BDENF (BVS), WoS, IRCTP(WHO), ClinicalsTrials.gov and PROSPERO databases were searched with no restriction on year or language. Preferred Reporting items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed.

resultsA total of 1429 participants from 17 studies were included. The meta-analysis found that ventrogluteal injection site had significant relation to lower pain in 9 studies (SMD = -0.63, 95% CI = -0.87, -0.39), bleeding in 4 studies (SMD = -3.46, 95% CI = -6.07, -0.86) and hematoma in 2 studies; after 48 h (SMD = -0.25, 95% CI = -0.39, -0.11), and after 72 h (SMD = -0.16, 95% CI = -0.26, -0.06), if it was compared with dorsogluteal site injection. No differences were found when comparing the possibility of intramuscular injections given into de subcutaneous tissue. In three studies, ventrogluteal site did not significantly reduce the risk of subcutaneous injection (OR 0,62, 95% CI = 0.16, 2.41).

Indexed as

Muscle, SkeletalSubcutaneous FatButtocksHumansInjections, IntramuscularSubcutaneous Tissueadverse effectsbuttocksdorsoglutealinjectionsintramuscularintramuscular/adverse effects*intramuscular/methods*nursingsubcutaneoussystematic reviewventrogluteal

Identifiers

PMID37452553
PMCPMC10415997
OpenAlexW4384401318

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.