Evidence map›Paper›PMID 37452421›Full record

ArticleBMC endocrine disorders2023

Vitamin D deficiency increases with age and adiposity in Emirati children and adolescents irrespective of type 1 diabetes mellitus: a case control study.

Maria Majeed, Mohsin Siddiqui, Nader Lessan

Abstract read
In one paragraph

Article in BMC endocrine disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maria Majeed *Imperial College London Diabetes Centre, Khaleej Al Arabi Street, PO Box 48338, Abu Dhabi, UAE.ORCID http://orcid.org/0000-0003-2634-6221
Mohsin Siddiqui *Imperial College London Diabetes Centre, Khaleej Al Arabi Street, PO Box 48338, Abu Dhabi, UAE.
Nader LessanImperial College London Diabetes Centre, Khaleej Al Arabi Street, PO Box 48338, Abu Dhabi, UAE. nlessan@icldc.ae.

Funding

Imperial College London Diabetes Centre, a Mubadala Health Company IREC008
6 · The paper itself

Abstract

backgroundAssociation of vitamin D (25(OH)D) deficiency with obesity and diabetes has been well-established in paediatric and adult populations. This study aims to report the association of 25(OH)D deficiency with body composition and prevalence of 25(OH)D deficiency in Emirati children and adolescents, who attended a diabetes centre in the United Arab Emirates.

methodsUsing Abu Dhabi Diabetes and Obesity Study cohort, type 1 diabetes (T1D) and normoglycaemic (NG) participants between 4-19 years of age were selected. WHO criteria were used to define 25(OH)D cut-offs: deficient (< 30 nmol/L), insufficient (30-50 nmol/L) and sufficient (> 50 nmol/L). Based on CDC recommendations, BMI percentile was categorised as underweight, normal weight, overweight and obesity.

resultsAfter age and sex matching, 148 T1D cases and 296 NG controls were identified. 25(OH)D deficiency was observed in 22.3% (n = 33) T1D and 40.5% (n = 120) NG participants. 25(OH)D levels were lower in adolescents (15 - 19 years) than children (4 - 7 years) in both T1D and NG groups (p = 0.018 vs p < 0.001). Females were more likely to be 25(OH)D deficient in both groups. Children and adolescents with BMI ≥ 95

conclusionVitamin D 25(OH)D deficiency is notably prevalent in Emirati children and adolescents despite adequate sunlight throughout the year. The prevalence was lower in those with T1D which may be indicative of treatment compliance in this population. This study also confirms important negative association of serum 25(OH)D levels with body mass and obesity in this population.

Indexed as

Diabetes Mellitus, Type 1Vitamin D DeficiencyAdiposityAdolescentAdultBody Mass IndexCase-Control StudiesChildFemaleHumansObesityPrevalenceUnited Arab EmiratesVitamin DVitamin D25(OH)DAdiposityEmirati Children and AdolescentsNormoglycaemiaObesityPaediatric populationType 1 Diabetes

Identifiers

PMID37452421
PMCPMC10347721

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.