Evidence map›Paper›PMID 37452342›Full record

ArticleAIDS research and therapy2023

What are the determinants of antiretroviral therapy adherence among stable people living with HIV? A cross-sectional study in Cambodia.

Sovannary Tuot, Jian Wei Sim, Michiko Nagashima-Hayashi, Pheak Chhoun, Alvin Kuo Jing Teo, Kiesha Prem, Siyan Yi

Open access · goldAbstract read
In one paragraph

Article in AIDS research and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 6 countries.

Sovannary TuotKHANA Center for Population Health Research, Phnom Penh, Cambodia.
Jian Wei SimSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, 12 Science Drive 2, #10- 01, 117549, Singapore, Singapore.
Michiko Nagashima-HayashiSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, 12 Science Drive 2, #10- 01, 117549, Singapore, Singapore.
Pheak ChhounKHANA Center for Population Health Research, Phnom Penh, Cambodia.
Alvin Kuo Jing TeoSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, 12 Science Drive 2, #10- 01, 117549, Singapore, Singapore.
Kiesha PremSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, 12 Science Drive 2, #10- 01, 117549, Singapore, Singapore.
Siyan YiKHANA Center for Population Health Research, Phnom Penh, Cambodia. siyan@nus.edu.sg.
National University Health System · SGNational University of Singapore · SGLondon School of Hygiene & Tropical Medicine · GBThe University of Tokyo · JP

Funding

L' Initiative / Expertise France 19-SB0765
6 · The paper itself

Abstract

backgroundUnderstanding context-specific determinants of antiretroviral therapy (ART) adherence is crucial for developing tailored interventions for improving health outcomes and achieving the UNAIDS' third 95% target. This cross-sectional study explores factors associated with ART adherence among stable people living with HIV on ART in Cambodia.

methodsWe used baseline survey data from a quasi-experimental study conducted in 2021. The participants were recruited from 20 ART clinics in nine provinces for face-to-face interviews. A structured questionnaire collected information on sociodemographic characteristics, ART adherence, perceived ART self-efficacy, mental health, quality of life, stigma, and discrimination. We conducted bivariate and multiple logistic regression analyses to identify factors associated with ART adherence.

resultsOut of the 4101 participants, 86.5% reported adhering to ART in the past two months. The adjusted odds of ART adherence were significantly higher among participants in older age groups than those aged 15-29, participants with elevated cholesterol than those without it, participants who exhibited strong self-efficacy in health responsibility to maintain life than those with poor self-efficacy in health responsibility, participants who scored < 3 on the stigma and discrimination scale than those who scored ≥ 3, participants who scored ≥ 42 on the mental component of the quality-of-life scale than those who scored < 42. The adjusted odds of ART adherence were significantly lower in participants who earned > 301 USD per month than those who earned ≤ 100 USD per month.

conclusionThe ART adherence rate among stable people living with HIV in this study was comparable to that of the general people living with HIV in Cambodia. The results suggest the need for innovative interventions to further reduce stigma and discrimination and strategies to improve the self-efficacy and mental health of people living with HIV to improve ART adherence.

Indexed as

HIV InfectionsAgedAnti-Retroviral AgentsCambodiaCross-Sectional StudiesHumansMedication AdherenceQuality of LifeAnti-Retroviral AgentsAdherenceAIDSAntiretroviral therapyAsiaPeople living with HIVTreatment outcome

Identifiers

PMID37452342
PMCPMC10347818
OpenAlexW4384298654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.