Evidence map›Paper›PMID 37452301›Full record

ArticleBMC nephrology2023

Impact of frequent intradialytic hypotension on quality of life in patients undergoing hemodialysis.

Jianhua Wang, Jing Yao, Xiaoye Zhu, Tingting Wang, Jianda Lu, Qiubo Wei, Jun Xue, Yuanhao Wu, Li You

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. A Narrative Summary of Strategies to Mitigate Intradialytic Hypotension in Poisoned Patients Requiring Extracorporeal Toxin Elimination.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2026
    Review
  4. Bioelectrical Impedance in Pediatric Dialysis: Clinical Applications, Limitations, and Opportunities.Hemodialysis international. International Symposium on Home Hemodialysis · 2026
    Review
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jianhua Wang *Department of Nephrology, Huashan Hospital Affiliated to Fudan University, Baoshan Branch, Shanghai, China.
Jing Yao *Department of Nephrology, Huashan Hospital Affiliated to Fudan University, Baoshan Branch, Shanghai, China.
Xiaoye Zhu *Department of Nephrology, Huashan Hospital Affiliated to Fudan University, Baoshan Branch, Shanghai, China.
Tingting WangDepartment of Nephrology, Huashan Hospital Affiliated to Fudan University, Baoshan Branch, Shanghai, China.
Jianda LuDepartment of Nephrology, Huashan Hospital Affiliated to Fudan University, Baoshan Branch, Shanghai, China.
Qiubo WeiDepartment of Nephrology, Huashan Hospital Affiliated to Fudan University, Baoshan Branch, Shanghai, China.
Jun XueDepartment of Nephrology, Huashan Hospital Affiliated to Fudan University, Baoshan Branch, Shanghai, China.
Yuanhao WuDepartment of Nephrology, Huashan Hospital Affiliated to Fudan University, Baoshan Branch, Shanghai, China.
Li YouDepartment of Nephrology, Huashan Hospital Affiliated to Fudan University, Baoshan Branch, Shanghai, China.
Fudan University · CNHuashan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntradialytic hypotension (IDH) is frequently accompanied by symptoms of nausea, dizziness, fatigue, muscle spasm, and arrhythmia, which can adversely impact the daily lives of patients who undergo hemodialysis and may lead to decreased quality of life (QoL). This study employed the KDQOL™-36 scale to evaluate the impact of frequent IDH, based on the definition determined by predialysis blood pressure (BP) and nadir systolic blood pressure (SBP) thresholds, on the QoL of patients.

methodsThis is a single center retrospective cohort study involving 160 hemodialysis patients. We enrolled adult patients with uremia who received routine hemodialysis (4 h/time, 3 times/week) from October 1, 2019, to September 30, 2021. Frequent IDH was defined as an absolute nadir SBP < 90 mmHg occurring in no less than 30% of hemodialysis sessions when predialysis SBP < 159 mmHg (or < 100 mmHg when predialysis BP ≥ 160 mmHg).The differences between patients with and without frequent IDH were compared using the independent t test, Kruskal‒Wallis test, or chi-square test. The primary visit was at month 36, and the remaining visits were exploratory outcomes.

resultsCompared to patients with infrequent IDH at baseline, those with frequent IDH had significantly lower scores on the symptoms and discomfort of kidney disease dimension at all follow-up points (P < 0.05). The symptoms and discomfort of kidney disease dimension were worse in patients with frequent IDH. Those with frequent IDH had a significantly poorer QoL regarding the dimensions of symptoms and discomfort of kidney disease and the impact of kidney disease on life.

conclusionsThe findings of the study suggest an association between frequent IDH and QoL dimensions of symptoms and discomfort of kidney disease and the impact of kidney disease on life dimension under the definition of frequent IDH.

Indexed as

HypotensionKidney Failure, ChronicAdultBlood PressureHumansQuality of LifeRenal DialysisRetrospective StudiesBlood pressure (BP)Intradialytic hypotension (IDH)PredialysisQuality of life (QoL)Systolic blood pressure (SBP)

Identifiers

PMID37452301
PMCPMC10347841
OpenAlexW4384342747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.