Evidence map›Paper›PMID 37452284›Full record

ReviewBMC ophthalmology2023

Severe macular complications in glaucoma: high-resolution multimodal imaging characteristics and review of the literature.

Hugo Lama, Michel Pâques, Emmanuelle Brasnu, Jade Vu, Céline Chaumette, Bénédicte Dupas, Christine Fardeau, Ismaël Chehaibou, Jean-François Rouland, Guillaume Besombes and 3 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Hugo LamaDepartment of Ophthalmology, Assistance Publique - Hôpitaux de Paris - Université Paris Saclay, 78, rue du Général Leclerc, Le Kremlin Bicêtre, 94275, France.
Michel PâquesDepartment of Ophthalmology, Quinze-Vingts National Eye Hospital, IHU Foresight, Paris, France.
Emmanuelle BrasnuDepartment of Ophthalmology, Quinze-Vingts National Eye Hospital, IHU Foresight, Paris, France.
Jade VuDepartment of Ophthalmology, Assistance Publique - Hôpitaux de Paris - Université Paris Saclay, 78, rue du Général Leclerc, Le Kremlin Bicêtre, 94275, France.
Céline ChaumetteDepartment of Ophthalmology, Quinze-Vingts National Eye Hospital, IHU Foresight, Paris, France.
Bénédicte DupasDepartment of Ophthalmology, Assistance Publique - Hôpitaux de Paris - Université Paris Saclay, 78, rue du Général Leclerc, Le Kremlin Bicêtre, 94275, France.
Christine FardeauDepartment of Ophthalmology, Assistance Publique - Hôpitaux de Paris - Université Paris Saclay, 78, rue du Général Leclerc, Le Kremlin Bicêtre, 94275, France.
Ismaël ChehaibouOphtalmopôle Cochin, APHP, Paris, France.
Jean-François RoulandDepartment of Ophthalmology, Hôpital Claude Huriez, CHRU, Lille, France.
Guillaume BesombesDepartment of Ophthalmology, Hôpital Claude Huriez, CHRU, Lille, France.
Marc LabetoulleDepartment of Ophthalmology, Assistance Publique - Hôpitaux de Paris - Université Paris Saclay, 78, rue du Général Leclerc, Le Kremlin Bicêtre, 94275, France.
Antoine LabbéDepartment of Ophthalmology, Quinze-Vingts National Eye Hospital, IHU Foresight, Paris, France.
Antoine RousseauDepartment of Ophthalmology, Assistance Publique - Hôpitaux de Paris - Université Paris Saclay, 78, rue du Général Leclerc, Le Kremlin Bicêtre, 94275, France. antoine.rousseau@aphp.fr.
Assistance Publique – Hôpitaux de Paris · FRCentre hospitalier national d'ophtalmologie des Quinze-Vingts · FRHôpital Claude Huriez · FRUniversité Paris-Saclay · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe imaging characteristics of severe macular complications occurring in glaucoma and discuss available treatments.

methodsRetrospective case series of glaucomatous patients with macular retinoschisis (MR) and/or serous retinal detachment (SRD). Patients underwent a complete ophthalmological examination and multimodal imaging including retinography, SD-OCT, fluorescein and indocyanine green angiography (FA & ICGA) and adaptive optics (AO).

resultsTen eyes (8 patients) were included. Initial BCVA was 1.04 ± 1.12 logMAR and IOP was 24.0 ± 9.3mmHg. All eyes presented with MR while SRD was present in 5 eyes (5 patients), with a central macular thickness of 573 ± 152 μm. FA and ICGA allowed to exclude leakage in all cases. A focal lamina cribrosa defect (LCD) was found in four eyes (4 patients) using OCT, with AO providing en-face visualization of the defect in one eye. Outer retinal hole was present in 3 eyes (3 patients). No visual improvement or resolution of the macular retinoschisis was observed in eyes with medical or surgical IOP control (N = 9). Vitrectomy with internal membrane limiting peeling and gas tamponade was performed in one eye with good visual results.

conclusionsMultimodal high-resolution imaging is essential to diagnose severe macular complications associated with advanced glaucoma.

Indexed as

GlaucomaRetinal DetachmentRetinal PerforationsRetinoschisisHumansMultimodal ImagingRetrospective StudiesTomography, Optical CoherenceVitrectomyAdaptive opticsGlaucomaHigh-resolution imagingMacular edemaRetinoschisisSerous retinal detachment

Identifiers

PMID37452284
PMCPMC10347769
OpenAlexW4384342787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.