ReviewNature reviews. Cardiology2024
Heart transplantation: advances in expanding the donor pool and xenotransplantation.
Review in Nature reviews. Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 42 citations in OpenAlex.
- Clinical translation and engineering challenges of soft robotic cardiac sleeves for heart failure.Nature communications · 2026Review
- High-urgency heart transplantation and outcome trade-offs: early post-transplant infection and mortality.ESC heart failure · 2026Article
- Potential pool of cardiothoracic organs from donors with HIV.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2026Article
- Scientific and Technical Considerations of the World's First Beating Heart Transplantation in a Human: An Operator's View.JACC. Case reports · 2026Article
- Mechanistic study of Shenge powder on myocardial hypertrophy and cardiac lymphatic intervention in TAC-induced mouse models.Frontiers in pharmacology · 2026Article
- Chronic heart failure and heart transplantation: The relationship between autonomic function and cardiac performance.World journal of transplantation · 2025Review
- Recent Trends in Hospitalizations for Infection in the First Year After Heart Transplantation.Annals of thoracic surgery short reports · 2025Article
- Characteristics and outcomes of thromboembolism following cardiac transplant: a multi-institutional retrospective study.Research and practice in thrombosis and haemostasis · 2025Article
- Electrically conductive biopolymer-based hydrogels and fibrous materials fabricated using 3D printing and electrospinning for cardiac tissue engineering.Bioactive materials · 2025Review
- In Vivo Targeted Reprogramming of Cardiac Fibroblasts for Heart Regeneration: Advances and Therapeutic Potential.Bioengineering (Basel, Switzerland) · 2025Review
- Microfluidics-Based Microcarriers for Live-Cell Delivery.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- A contemporary simple risk score for prediction of severe acute kidney injury after heart transplantation.ESC heart failure · 2025Article
- Review
- Expanding the Donor Pool.Methodist DeBakey cardiovascular journal · 2025Review
- Claudin-2 enhances human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells by modulating antibody binding and complement activation.Frontiers in immunology · 2025Article
- Economic Burden and Healthcare Trajectories of Patients Awaiting Heart Transplantation in a French Tertiary Center.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- Commentary: Molecular responses in pig heart to human xenotransplantation unveiled by longitudinal multi-omic profiling.Clinical and translational medicine · 2025Article
- Platelet and Erythrocyte Membranes Coassembled Biomimetic Nanoparticles for Heart Failure Treatment.ACS nano · 2024Article
- Clinical Outcomes and Risk Factors of Heart Transplantation Patients Experiencing Gastrointestinal Bleeding.Biomedicines · 2024Article
- Cardiac Loading using Passive Left Atrial Pressurization and Passive Afterload for Graft Assessment.Journal of visualized experiments : JoVE · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Approximately 65 million adults globally have heart failure, and the prevalence is expected to increase substantially with ageing populations. Despite advances in pharmacological and device therapy of heart failure, long-term morbidity and mortality remain high. Many patients progress to advanced heart failure and develop persistently severe symptoms. Heart transplantation remains the gold-standard therapy to improve the quality of life, functional status and survival of these patients. However, there is a large imbalance between the supply of organs and the demand for heart transplants. Therefore, expanding the donor pool is essential to reduce mortality while on the waiting list and improve clinical outcomes in this patient population. A shift has occurred to consider the use of organs from donors with hepatitis C virus, HIV or SARS-CoV-2 infection. Other advances in this field have also expanded the donor pool, including opt-out donation policies, organ donation after circulatory death and xenotransplantation. We provide a comprehensive overview of these various novel strategies, provide objective data on their safety and efficacy, and discuss some of the unresolved issues and controversies of each approach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.