Evidence map›Paper›PMID 37452116›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2024

Trends in COVID-19 diagnoses and outcomes in infants hospitalized in the neonatal intensive care unit.

Elizabeth B Heyward, Reese H Clark, P Brian Smith, Daniel K Benjamin, Kanecia O Zimmerman, Kaashif A Ahmad, Courtney K Blackwell, Hannah Won, Rachel Ssengonzi, Avi Belbase and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Elizabeth B HeywardDepartment of Pediatrics, Duke University, Durham, NC, USA.
Reese H ClarkPediatrix Center for Research, Education, Quality, and Safety, Sunrise, FL, USA.ORCID 0000-0002-7363-4640
P Brian SmithDepartment of Pediatrics, Duke University, Durham, NC, USA.
Daniel K BenjaminDepartment of Pediatrics, Duke University, Durham, NC, USA.
Kanecia O ZimmermanDepartment of Pediatrics, Duke University, Durham, NC, USA.
Kaashif A AhmadPediatrix Center for Research, Education, Quality, and Safety, Sunrise, FL, USA.
Courtney K BlackwellDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Hannah WonDuke Clinical Research Institute, Durham, NC, USA.
Rachel SsengonziDuke Clinical Research Institute, Durham, NC, USA.
Avi BelbaseDuke Clinical Research Institute, Durham, NC, USA.
Courage O NdalamaDuke Clinical Research Institute, Durham, NC, USA.
Jennifer AnDuke Clinical Research Institute, Durham, NC, USA.
Ogugua NwaezeigweDuke Clinical Research Institute, Durham, NC, USA.
Rachel G GreenbergDepartment of Pediatrics, Duke University, Durham, NC, USA. rachel.greenberg@duke.edu.ORCID 0000-0003-4156-8543
Clinical Research Institute · USDuke University · USNorthwestern University · USUrology San Antonio · US

Funding

All of Us Research Program Data and Research CenterOT2OD035404 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Melissa Basford, DAVID GLAZER · 2023 to 2026
$210.4M
COVID-19 Supplement - Center for Innovative TRIals in ChilDrEN and AdulTs (TRIDENT)U24TR001608 · NCATS · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K. · 2016 to 2022
$177.0M
Improving Clinical trial Education, Recruitment, and Enrollment at CTSA Hubs (I-CERCH) - HEAL SupplementU24TR001579 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HARRIS, PAUL A., WILKINS, CONSUELO HOPKINS · 2016 to 2022
$34.1M
NIH Summer Research Experience Programs (R25)R25HD076475 · NICHD · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K. · 2013 to 2023
$1.1M
NCATS NIH HHS U24 TR001579NCATS NIH HHS U24 TR001608NICHD NIH HHS R25 HD076475NIH HHS OT2 OD035404
6 · The paper itself

Abstract

objectiveCharacterize the prevalence of coronavirus disease 2019 (COVID-19) diagnosis among mothers with infants hospitalized in 294 neonatal intensive care units (NICUs), and demographics and outcomes of infants with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure in utero. STUDY

designCohort study of infants discharged from NICUs 01/2020-09/2021. We defined groups based on infant diagnosis, infant testing, and maternal SARS-CoV-2 infection status. We compared demographics, clinical characteristics, and outcomes.

resultsOf 150,924 infants, 94% had no COVID-related diagnosis or test; 247 (0.2%) infants tested positive for COVID-19 and were more likely to require mechanical ventilation. Infants with unknown maternal status and negative testing were more commonly premature, outborn, and had longer hospitalizations.

conclusionIn this large cohort of hospitalized infants, most had no known exposure to COVID-19. Adverse outcomes and mortality were rare. Further studies are needed to evaluate the long-term effects of COVID-19 in this population.

Indexed as

COVID-19Pregnancy Complications, InfectiousCohort StudiesCOVID-19 TestingFemaleHumansInfantInfant, NewbornIntensive Care Units, NeonatalPregnancySARS-CoV-2

Identifiers

PMID37452116
PMCPMC11464098
OpenAlexW4384398017

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.