Evidence map›Paper›PMID 37452082›Full record

ArticleScientific reports2023

Phytochemical profiling and cytotoxic potential of Arnebia nobilis root extracts against hepatocellular carcinoma using in-vitro and in-silico approaches.

Asia Kiran, Awais Altaf, Muhammad Sarwar, Arif Malik, Tahir Maqbool, Qurban Ali

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Phytochemical Profiling and Anticancer Potential ofAnti-cancer agents in medicinal chemistry · 2026
    Article
  3. Article
  4. Article
  5. Frontiers in nutrition · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Asia KiranInstitute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, 54300, Pakistan.
Awais AltafInstitute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, 54300, Pakistan. awaisaltaf362@yahoo.com.
Muhammad SarwarInstitute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, 54300, Pakistan.
Arif MalikInstitute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, 54300, Pakistan.
Tahir MaqboolInstitute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, 54300, Pakistan.
Qurban AliDepartment of Plant Breeding and Genetics, Faculty of Agricultural Sciences, University of the Punjab, Lahore, Pakistan. saim1692@gmail.com.
University of Lahore · PKUniversity of the Punjab · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma is the fifth most prevalent cancer worldwide. The emergence of drug resistance and other adverse effects in available anticancer options are challenging to explore natural sources. The current study was designed to decipher the Arnebia nobilis (A. nobilis) extracts for detecting phytochemicals, in-vitro evaluation of antioxidative and cytotoxic potentials, and in-silico prediction of potent anticancer compounds. The phytochemical analysis revealed the presence of flavonoids, phenols, tannins, alkaloids, quinones, and cardiac glycosides, in the ethanol (ANE) and n-hexane (ANH) extracts of A. nobilis. ANH extract exhibited a better antioxidant potential to scavenge DPPH, nitric oxide and superoxide anion radicals than ANE extract, which showed better potential only against H

Indexed as

Antineoplastic AgentsCarcinoma, HepatocellularLiver NeoplasmsAntioxidantsFlavonoidsHumansHydrogen PeroxideMolecular Docking SimulationPhytochemicalsPlant ExtractsAntineoplastic AgentsAntioxidantsFlavonoidsHydrogen PeroxidePhytochemicalsPlant Extracts

Identifiers

PMID37452082
PMCPMC10349071
OpenAlexW4384339903

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.