Evidence map›Paper›PMID 37451516›Full record

ArticleJournal of substance use and addiction treatment2023

The Phenotype of Recovery X: Associations between delay discounting, regulatory flexibility, and remission from substance use disorder.

Candice L Dwyer, Allison N Tegge, William H Craft, Devin C Tomlinson, Liqa N Athamneh, Warren K Bickel

Abstract read
In one paragraph

Article in Journal of substance use and addiction treatment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Mental health and physical activity · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Candice L DwyerFralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, VA, USA; Department of Psychology, Virginia Tech, Blacksburg, VA, USA.
Allison N TeggeFralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, VA, USA; Department of Statistics, Virginia Tech, Blacksburg, VA, USA.
William H CraftFralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, VA, USA; Graduate Program in Translational Biology, Medicine, and Health, Virginia Tech, USA.
Devin C TomlinsonFralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, VA, USA; Graduate Program in Translational Biology, Medicine, and Health, Virginia Tech, USA.
Liqa N AthamnehFralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, VA, USA.
Warren K BickelFralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, VA, USA. Electronic address: wkbickel@vtc.vt.edu.

Funding

Longitudinal Study of Recovery: Psychosocial Functioning, Relapse, and Neuro-Behavioral MarkersR01AA029135 · NIAAA · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Jungmeen Kim-Spoon, Allison N Tegge · 2022 to 2026
$3.5M
An Experimental Medicine Approach for the Mechanistic Understanding of Cocaine Use Disorder: Reinforcer PathologyR01DA054216 · NIDA · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI STEPHEN M LACONTE · 2022 to 2026
$3.5M
Testing Reinforcer Pathology: Mechanisms and Interventions to Change Alcohol ValuationR01AA027381 · NIAAA · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI LACONTE, STEPHEN M · 2019 to 2023
$3.5M
NIAAA NIH HHS R01 AA027381NIAAA NIH HHS R01 AA029135NIDA NIH HHS R01 DA054216
6 · The paper itself

Abstract

introductionDelay discounting (DD) and self-regulation are important predictors of substance use disorder (SUD) outcomes. Further, regulatory flexibility (RF; i.e., selecting, monitoring, and adapting coping techniques based on contextual demands) is related to psychological resilience. However, studies have yet to examine associations among DD, RF, and remission from SUDs among individuals in recovery.

methodsIndividuals (N = 148) in SUD recovery completed the Context Sensitivity Index (CSI), the Flexible Regulation of Emotional Expression (FREE) Scale, and the Perceived Ability to Cope with Trauma (PACT) Scale to assess RF and, an $1000 hypothetical reward Adjusting Amount Delay Discounting Task. The study considered individuals to be in remission from SUD if they did not endorse any SUD DSM-5 symptom other than craving (except tobacco use disorder) in the past three months. The study team used t-tests to examine differences in RF and DD by remission status. Univariate linear regressions were used to examine the relationship between RF and DD. Finally, mediation models examined the dynamic relationship among DD, RF, and remission status.

resultsRemitted individuals (n = 82) had significantly lower DD (i.e., greater preference for larger, later rewards) rates (p < .001) and higher context sensitivity (p < .001) and coping flexibility (p < .001). The study found significant negative associations between DD and context sensitivity (p = .008), coping flexibility (p = .002), and emotion regulation flexibility (p < .001). Finally, context sensitivity (p = .023) and coping flexibility (p = .009) mediated the relationship between DD and SUD remission.

conclusionsResults suggest that individuals in recovery with broader temporal windows can better identify contextual demands and flexibly cope, contributing to improved SUD recovery outcomes.

Indexed as

Delay DiscountingSubstance-Related DisordersAdaptation, PsychologicalHumansPhenotypeRewardCoping flexibilityDelay discountingRecoveryRegulatory flexibilitySubstance use disorder

Identifiers

PMID37451516
PMCPMC10787043

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.