Evidence map›Paper›PMID 37450948›Full record

ReviewCurrent opinion in pharmacology2023

Adenosine signaling as target in cardiovascular pharmacology.

Luca Antonioli, Matteo Fornai, Carolina Pellegrini, Pál Pacher, György Haskó

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Luca AntonioliDepartment of Clinical and Experimental Medicine, University of Pisa, 56126, Pisa, Italy.
Matteo FornaiThe Institution is Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Carolina PellegriniThe Institution is Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Pál PacherLaboratory of Cardiovascular Physiology and Tissue Injury, National Institutes of Health/NIAAA, Bethesda, MD, 20892, USA.
György HaskóDepartment of Anesthesiology, Columbia University, New York, NY, 10032, USA. Electronic address: gh2503@cumc.columbia.edu.
University of Pisa · ITColumbia University · USNational Institutes of Health · US

Funding

Mechanism of oxidative/nitrosative stress and inflammation-induced tissue injuryZIAAA000375 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI PACHER, PAL · 2009 to 2025
$27.8M
Purinergic signaling in trauma and sepsisR01GM066189 · NIGMS · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI HASKO, GEORGE · 2002 to 2020
$4.7M
Neutrophil A2A receptors in sepsisR01HL158519 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HASKO, GEORGE · 2021 to 2024
$2.1M
Purinergic signaling in granuloma-forming Th2 immunityR01DK113790 · NIDDK · RBHS-NEW JERSEY MEDICAL SCHOOL · PI GAUSE, WILLIAM CLARK, HASKO, GEORGE · 2017 to 2020
$1.9M
NHLBI NIH HHS R01 HL158519NIDDK NIH HHS R01 DK113790NIGMS NIH HHS R01 GM066189
6 · The paper itself

Abstract

Increasing evidence demonstrated the relevance of adenosine system in the onset and development of cardiovascular diseases, such as hypertension, myocardial infarct, ischemia, hypertension, heart failure, and atherosclerosis. In this regard, intense research efforts are being focused on the characterization of the pathophysiological significance of adenosine, acting at its membrane receptors named A

Indexed as

Cardiovascular DiseasesHypertensionAdenosineHumansReceptor, Adenosine A2AReceptor, Adenosine A2BAdenosineReceptor, Adenosine A2AReceptor, Adenosine A2B

Identifiers

PMID37450948
PMCPMC10527223
OpenAlexW4384028405

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.