Trial reportAmerican journal of respiratory and critical care medicine2023
A Double-Blind, Randomized, Placebo-controlled Trial of Long-Term Doxycycline Therapy on Exacerbation Rate in Patients with Stable Chronic Obstructive Pulmonary Disease.
Trial report in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 12 citations in OpenAlex.
- Adjunctive Short-Wave Diathermy to High-Frequency Chest Wall Oscillation for Acute Exacerbation of COPD: A Randomized Controlled Trial.Canadian respiratory journal · 2026Trial
- Revealing Biomarkers and Candidate Drugs for Chronic Obstructive Pulmonary Disease Using Bioinformatics and Deep Learning.International journal of chronic obstructive pulmonary disease · 2026Article
- Predictive value analysis of diaphragmatic ultrasound evaluation for mechanical ventilation outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease.BMC pulmonary medicine · 2025Article
- Observational
- Efficacy of Prophylactic Antibiotics in COPD: A Systematic Review.Antibiotics (Basel, Switzerland) · 2024Review
- Reply to Martinez-GarciaAmerican journal of respiratory and critical care medicine · 2023Article
- Long-Term Doxycycline Therapy for Stable Chronic Obstructive Pulmonary Disease: Do the Benefits Outweigh the Drawbacks?American journal of respiratory and critical care medicine · 2023Article
- Microbiological Monitoring in Therapeutic Trials in Chronic Obstructive Pulmonary Disease.American journal of respiratory and critical care medicine · 2023Article
- Revisiting the Use of Antibiotics to Prevent COPD Exacerbation: Is Doxycycline the Answer?American journal of respiratory and critical care medicine · 2023Article
- Current Evidence on the Usefulness of Potential Therapies in the Prevention of COPD Exacerbations: Beyond the Use of Bronchodilator Therapy and Inhaled Corticosteroids.Open respiratory archivesReview
Corrections and comments
- Commented on by
- Commented on by
- Commented on by
Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.