ArticleScience immunology2023
Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease.
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Article in Science immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
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Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Celiac Disease: Cytokine Profile of Intraepithelial Gamma Delta T Cells in Disease Severity.Cells · 2026Article
- The long noncoding RNA lnc13 restrains inflammatory responses to maintain oral tolerance to gluten.Nature immunology · 2026Article
- γδ T Cells in Autoinflammatory Diseases.Cells · 2026Review
- T cell receptors for antigen on intraepithelial cytolytic T lymphocytes in celiac disease engage enterocyte HLA-E and HLA-B.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Translational potential of γδ T cells in hematologic diseases: from immunobiology to therapeutic innovation.Frontiers in immunology · 2026Review
- Gut mucosal immune responses - Implications for celiac disease and food allergy.Seminars in immunology · 2025Review
- Intraepithelial Lymphocytes and LAIR1 Expression in Celiac Disease.Biomedicines · 2025Article
- Transcriptomics and eQTLs reveal inflammatory heterogeneity in the duodenal lining in coeliac disease.Genes and immunity · 2025Article
- Mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis.Nature immunology · 2025Article
- Is immune effector cell-associated enterocolitis a CAR T-cell lymphoproliferative disorder?Blood cancer journal · 2025Article
- Immune-epithelial-stromal networks define the cellular ecosystem of the small intestine in celiac disease.Nature immunology · 2025Article
- Conserved developmental rewiring of the TCR signalosome drives tolerance in innate-like lymphocytes.bioRxiv : the preprint server for biology · 2025Article
- Redefining the high variable genes by optimized LOESS regression with positive ratio.BMC bioinformatics · 2025Article
- Shared Genetics in Celiac Disease and Inflammatory Bowel Disease Specify a Greater Role for Intestinal Epithelial Cells.International journal of molecular sciences · 2025Review
- Heterogeneity of CD8αα intraepithelial lymphocytes is transcriptionally conserved between TCRαβ and TCRγδ cell lineages.Frontiers in immunology · 2025Article
- Coeliac disease as a model for understanding multiple sclerosis.Nature reviews. Neurology · 2024Review
- CD4 T cells restricted to DRB1*15:01 recognize two Epstein-Barr virus glycoproteins capable of intracellular antigen presentation.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Association of HLA-DQ4/5 genotype polymorphisms with celiac disease in a group of children in Southwest Iran: A case-control study.Health science reports · 2024Article
- New Insights on Genes, Gluten, and Immunopathogenesis of Celiac Disease.Gastroenterology · 2024Review
- PD-1 defines a distinct, functional, tissue-adapted state in Vδ1Nature cancer · 2024Article
Corrections and comments
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Authors and funding
21 authors at 2 institutions in 1 country.
Adam KornbergColumbia Center for Translational Immunology, Columbia University, New York, NY, USA.ORCID 0000-0002-8099-9699
Theo BotellaColumbia Center for Human Development, Columbia University, New York, NY, USA.ORCID 0000-0003-0331-2491
Christine S MoonColumbia Center for Translational Immunology, Columbia University, New York, NY, USA.ORCID 0000-0001-8717-2435
Samhita RaoColumbia Center for Translational Immunology, Columbia University, New York, NY, USA.ORCID 0000-0003-4155-7158
Jared GelbsColumbia Center for Translational Immunology, Columbia University, New York, NY, USA.ORCID 0009-0004-8575-3155
Liang ChengColumbia Center for Human Development, Columbia University, New York, NY, USA.
Jonathan MillerColumbia Center for Human Development, Columbia University, New York, NY, USA.ORCID 0000-0002-8189-5453
Alyssa M BacarellaDepartment of Pediatrics, Columbia University, New York, NY, USA.
Javier A García-VilasColumbia Center for Translational Immunology, Columbia University, New York, NY, USA.ORCID 0000-0003-0700-5069
Justin VargasDepartment of Medicine, Digestive and Liver Diseases, Columbia University, New York, NY, USA.ORCID 0009-0009-5123-9904
Xuechen YuCeliac Disease Center, Columbia University, New York, NY, USA.ORCID 0000-0001-5659-1418
Izabela KrupskaDepartment of Systems Biology, Columbia University, New York, NY, USA.ORCID 0009-0008-8111-6780
Erin BushDepartment of Systems Biology, Columbia University, New York, NY, USA.ORCID 0000-0001-7038-2321
Reuben Garcia-CarrasquilloDepartment of Medicine, Digestive and Liver Diseases, Columbia University, New York, NY, USA.ORCID 0000-0002-8970-8544
Benjamin LebwohlDepartment of Medicine, Digestive and Liver Diseases, Columbia University, New York, NY, USA.
Suneeta KrishnareddyDepartment of Medicine, Digestive and Liver Diseases, Columbia University, New York, NY, USA.
Suzanne LewisDepartment of Medicine, Digestive and Liver Diseases, Columbia University, New York, NY, USA.ORCID 0000-0002-6651-4499
Peter H R GreenDepartment of Medicine, Digestive and Liver Diseases, Columbia University, New York, NY, USA.ORCID 0000-0001-6839-9634
Govind BhagatCeliac Disease Center, Columbia University, New York, NY, USA.ORCID 0000-0001-6250-048X
Kelley S YanColumbia Center for Human Development, Columbia University, New York, NY, USA.ORCID 0000-0001-9826-7261
Arnold HanColumbia Center for Translational Immunology, Columbia University, New York, NY, USA.ORCID 0000-0002-2667-5335
Columbia University Irving Medical Center · USColumbia University · US
Funding
The Organoid and Cell Culture CoreP30DK132710 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Robert F. Schwabe · 2022 to 2026
$7.2MThe Columbia University Training Program in Lung ScienceT32HL105323 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Jahar Bhattacharya, Wellington V. Cardoso · 2011 to 2026
$4.7MDirecting Cell Fate Along the Intestinal Enteroendocrine LineageDP2DK128801 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI YAN, KELLEY · 2020 to 2020
$2.4MIntestinal Stem Cell Function During Aging and Tumor InitiationR01AG067014 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI YAN, KELLEY · 2020 to 2024
$2.3MColumbia University Graduate Training Program in Microbiology and ImmunologyT32AI106711 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Nicholas Arpaia, Uttiya Basu · 2014 to 2026
$2.1MThe Intraepithelial T cell Response in Celiac DiseaseK08DK100739 · NIDDK · STANFORD UNIVERSITY · PI HAN, ARNOLD · 2015 to 2019
$787kCytotoxic T cells in Ulcerative ColitisR03DK121026 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HAN, ARNOLD · 2019 to 2020
$162kA novel genetic model for congenital obstructive nephropathyR03DK100738 · NIDDK · UNIVERSITY OF HAWAII AT MANOA · PI FOGELGREN, BENJAMIN C. · 2014 to 2015
$152kNHLBI NIH HHS T32 HL105323NIAID NIH HHS T32 AI106711NIA NIH HHS R01 AG067014NIDDK NIH HHS DP2 DK128801NIDDK NIH HHS K08 DK100739NIDDK NIH HHS P30 DK132710NIDDK NIH HHS R03 DK100738NIDDK NIH HHS R03 DK121026
Abstract
Celiac disease (CD) is an autoimmune disease in which intestinal inflammation is induced by dietary gluten. The means through which gluten-specific CD4
Indexed as
Celiac DiseaseIntraepithelial LymphocytesGlutensHumansInflammationT-Lymphocytes, CytotoxicGlutens
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What OpenQuestion holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.