Evidence map›Paper›PMID 37450107›Full record

ArticleEuropean geriatric medicine2023

Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE).

Giulia Ogliari, Jesper Ryg, Karen Andersen-Ranberg, Lasse Lybecker Scheel-Hincke, Jemima T Collins, Alison Cowley, Claudio Di Lorito, Vicky Booth, Roelof A J Smit, Ralph K Akyea and 4 more

Open access · hybridAbstract read
In one paragraph

Article in European geriatric medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  3. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Giulia OgliariDepartment of Health Care of Older People (HCOP), Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Derby Road, Nottingham, Nottinghamshire, NG7 2UH, UK.ORCID 0000-0001-8273-3619
Jesper RygDepartment of Geriatric Medicine, Odense University Hospital, Odense, Denmark.ORCID 0000-0002-8641-3062
Karen Andersen-RanbergDepartment of Geriatric Medicine, Odense University Hospital, Odense, Denmark.ORCID 0000-0003-1970-7076
Lasse Lybecker Scheel-HinckeUnit for Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, 5000, Odense, Denmark.ORCID 0000-0002-4672-8959
Jemima T CollinsDepartment of Health Care of Older People (HCOP), Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Derby Road, Nottingham, Nottinghamshire, NG7 2UH, UK.ORCID 0000-0003-3865-7334
Alison CowleyUniversity of Nottingham, Nottingham, UK.ORCID 0000-0001-6858-475X
Claudio Di LoritoDivision of Primary Care and Population Health, University College London, London, UK.ORCID 0000-0002-8953-0117
Vicky BoothUniversity of Nottingham, Nottingham, UK.ORCID 0000-0002-5338-0196
Roelof A J SmitNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Building 7 (Maersk Tower), 2200, Copenhagen, Denmark.ORCID 0000-0001-9822-6726
Ralph K AkyeaPrimary Care Stratified Medicine, School of Medicine, University of Nottingham, Nottingham, UK.ORCID 0000-0003-4529-8237
Nadeem QureshiPrimary Care Stratified Medicine, School of Medicine, University of Nottingham, Nottingham, UK.ORCID 0000-0003-4909-0644
David A WalshPain Centre Versus Arthritis, University of Nottingham, Nottingham, UK.ORCID 0000-0002-6316-5692
Rowan H HarwoodDepartment of Health Care of Older People (HCOP), Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Derby Road, Nottingham, Nottinghamshire, NG7 2UH, UK. rowan.harwood@nottingham.ac.uk.ORCID 0000-0002-4920-6718
Tahir MasudDepartment of Health Care of Older People (HCOP), Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Derby Road, Nottingham, Nottinghamshire, NG7 2UH, UK.ORCID 0000-0003-1061-2898
Nottingham University Hospitals NHS Trust · GBUniversity of Nottingham · GBUniversity of Southern Denmark · DKUniversity College London · GBUniversity of Copenhagen · DK

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Understanding and Improving Healthcare Decision-Making and Outcomes for People Living with Alzheimer's Disease and Related DementiasP01AG005842 · NIA · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI JOSEPH J DOYLE · 1986 to 2026
$56.5M
WEALTH DISPARITIES AMONG MATURE AND OLDER ADULTSP01AG008291 · NIA · RAND CORPORATION · PI HURD, MICHAEL D · 1989 to 2018
$19.4M
RAND CENTER FOR THE STUDY OF AGINGP30AG012815 · NIA · RAND CORPORATION · PI HURD, MICHAEL D · 1999 to 2020
$13.7M
DEVELOPING AN ISRAELI VERSION OF THE HRS/SHARE PROJECTR21AG025169 · NIA · HEBREW UNIVERSITY OF JERUSALEM · PI LITWIN, HOWARD · 2004 to 2006
$297k
NIA NIH HHS P01 AG005842NIA NIH HHS P01 AG008291NIA NIH HHS P30 AG012815NIA NIH HHS R21 AG025169NIA NIH HHS U01 AG009740
6 · The paper itself

Abstract

purposeTo investigate the longitudinal associations between pain and depressive symptoms in adults.

methodsProspective cohort study on data from 28,515 community-dwelling adults ≥ 50 years, free from depression at baseline (Wave 5), with follow-up in Wave 6 of the Survey of Health, Ageing and Retirement in Europe (SHARE). Significant depressive symptoms were defined by a EURO-D score ≥ 4. The longitudinal association between baseline pain intensity and significant depressive symptoms at follow-up was analysed using logistic regression models; odds ratios (ORs) and confidence intervals (CI) were calculated, adjusting for socio-demographic and clinical factors, physical inactivity, loneliness, mobility and functional impairments.

resultsMean age was 65.4 years (standard deviation 9.0, range 50-99); 14,360 (50.4%) participants were women. Mean follow-up was 23.4 (standard deviation 3.4) months. At baseline, 2803 (9.8%) participants reported mild pain, 5253 (18.4%) moderate pain and 1431 (5.0%) severe pain. At follow-up, 3868 (13.6%) participants-1451 (10.3%) men and 2417 (16.8%) women-reported significant depressive symptoms. After adjustment, mild, moderate and severe baseline pain, versus no pain, were associated with an increased likelihood of significant depressive symptoms at follow-up: ORs (95% CI) were 1.20 (1.06-1.35), 1.32 (1.20-1.46) and 1.39 (1.19-1.63), respectively. These associations were more pronounced in men compared to women, and consistent in participants aged 50-64 years, those without mobility or functional impairment, and those without loneliness at baseline.

conclusionHigher baseline pain intensity was longitudinally associated with a greater risk of significant depressive symptoms at 2-year follow-up, in community-dwelling adults without baseline depression.

Indexed as

DepressionRetirementAgedAgingEuropeFemaleFollow-Up StudiesHealth SurveysHumansIndependent LivingLongitudinal StudiesMaleMiddle AgedPainPain MeasurementProspective StudiesAgeingDepressive symptomsLonelinessPainPopulation-based prospective studySex-differences

Identifiers

PMID37450107
PMCPMC10587243
OpenAlexW4384297943

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.