Evidence map›Paper›PMID 37449937›Full record

ArticlePediatric blood & cancer2023

Children's Oncology Group's 2023 blueprint for research: Epidemiology.

Philip J Lupo, Erin L Marcotte, Michael E Scheurer, Jenny N Poynter, Logan G Spector, COG Epidemiology Committee

Open access · bronzeAbstract read
In one paragraph

Article in Pediatric blood & cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Philip J LupoDivision of Hematology-Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0003-0978-5863
Erin L MarcotteDivision of Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Michael E ScheurerDivision of Hematology-Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
Jenny N PoynterDivision of Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Logan G SpectorDivision of Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
COG Epidemiology CommitteeDivision of Hematology-Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
University of Minnesota · USBaylor College of Medicine · US

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
COG FOREIGN ACCRUALU10CA098543 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI ADAMSON, PETER C. · 2003 to 2013
$335.5M
COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
Children's Oncology Group Statistics &Data Center GrantU10CA098413 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI DEVIDAS, MEENAKSHI · 2003 to 2013
$67.5M
The Genetic Basis of Neuroblastoma TumorigenesisR01CA124709 · NCI · CHILDREN'S HOSP OF PHILADELPHIA · PI MARIS, JOHN M · 2008 to 2017
$6.3M
The PreVAIL-kIds Common ProtocolR33HD105593 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI ALLEN, CARL E, ANNAPRAGADA, ANANTH V · 2023 to 2023
$6.3M
Molecular epidemiology of acute lymphoblastic leukemia in children with Down syndromeR01CA249867 · NCI · BAYLOR COLLEGE OF MEDICINE · PI LUPO, PHILIP, RABIN, KAREN R · 2020 to 2024
$4.2M
Molecular Epidemiology of Pediatric Germ Cell TumorsR01CA151284 · NCI · UNIVERSITY OF MINNESOTA · PI POYNTER, JENNY N. · 2011 to 2015
$3.4M
Molecular Epidemiology of Langerhans Cell Histiocytosis: Evaluating the Impact of SMAD6 and Genetic Ancestry on Disease RiskR01CA233719 · NCI · BAYLOR COLLEGE OF MEDICINE · PI ALLEN, CARL E, SCHEURER, MICHAEL E. · 2019 to 2023
$3.2M
Genetic Risk Factors for Ewing's SarcomaR01CA161780 · NCI · UNIVERSITY OF UTAH · PI SCHIFFMAN, JOSHUA DAVID · 2012 to 2016
$3.0M
Backtracking Leukemia-Typical Somatic Alterations in Cord Blood at Single-cell ResolutionR01CA262012 · NCI · UNIVERSITY OF MINNESOTA · PI DE SMITH, ADAM, SPECTOR, LOGAN G. · 2021 to 2025
$2.9M
Genetic Susceptibility Factors in the Etiology of NeuroblastomaR01CA132887 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI OLSHAN, ANDREW · 2008 to 2012
$2.8M
NCI NIH HHS R01 CA124709NCI NIH HHS R01 CA132887NCI NIH HHS R01 CA151284NCI NIH HHS R01 CA161780NCI NIH HHS R01 CA233719NCI NIH HHS R01 CA249867NCI NIH HHS R01 CA262012NCI NIH HHS R01 CA292941NCI NIH HHS R03 CA272955NCI NIH HHS U01 CA122371NCI NIH HHS U10 CA098413NCI NIH HHS U10 CA098543NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899NICHD NIH HHS R33 HD105593NIH HHS R01CA124709NIH HHS R01CA132887NIH HHS R01CA151284NIH HHS R01CA161780NIH HHS R01CA233719NIH HHS R01CA262012NIH HHS R03CA272955NIH HHS U01CA122371NIH HHS U10CA098413NIH HHS U10CA098543NIH HHS U10CA180886NIH HHS U10CA180899
6 · The paper itself

Abstract

The Children's Oncology Group (COG) Epidemiology Committee has a primary focus on better understanding the etiologies of childhood cancers. Over the past 10 years, the committee has leveraged the Childhood Cancer Research Network, and now more recently Project:EveryChild (PEC), to conduct epidemiologic assessments of various childhood cancers, including osteosarcoma, neuroblastoma, germ cell tumors, Ewing sarcoma, rhabdomyosarcoma, and Langerhans cell histiocytosis. More recent studies have utilized questionnaire data collected as part of PEC to focus on specific characteristics and/or features, including the presence of congenital disorders and the availability of stored cord blood. Members of the COG Epidemiology Committee have also been involved in other large-scale National Institutes of Health efforts, including the Childhood Cancer Data Initiative and the Gabriella Miller Kids First Pediatric Research Program, which are improving our understanding of the factors associated with childhood cancer risk. Future plans will focus on addressing questions surrounding health disparities, utilizing novel biospecimens in COG epidemiology studies, exploring the role of environmental factors on the etiologies and outcomes of childhood cancer, collaborating with other COG committees to expand the role of epidemiology in childhood cancer research, and building new epidemiologic studies from the Molecular Characterization Initiative-all with the ultimate goal of developing novel prevention and intervention strategies for childhood cancer.

Indexed as

Bone NeoplasmsNeoplasmsOsteosarcomaRhabdomyosarcomaSarcoma, EwingChildHumansMedical Oncologycancer geneticsepidemiologypediatric oncology

Identifiers

PMID37449937
PMCPMC10519152
OpenAlexW4384301209

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.