Evidence map›Paper›PMID 37449870›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2023

Neurovascular and hemodynamic responses to mental stress and exercise in severe COVID-19 survivors.

Diego Faria, Renata Moll-Bernardes, Laura Testa, Camila M V Moniz, Erika C Rodrigues, Jose M Mota, Francis R Souza, Maria Janieire N N Alves, Bruna E Ono, João E Izaias and 13 more

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Evaluation of myocardial work and exercise capacity in patients recovered from the severe form of COVID-19.International journal of cardiology. Cardiovascular risk and prevention · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 5 institutions in 2 countries.

Diego FariaD'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
Renata Moll-BernardesD'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
Laura TestaD'Or Institute for Research and Education (IDOR), São Paulo, Brazil.
Camila M V MonizD'Or Institute for Research and Education (IDOR), São Paulo, Brazil.
Erika C RodriguesD'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
Jose M MotaD'Or Institute for Research and Education (IDOR), São Paulo, Brazil.ORCID 0000-0001-9510-6956
Francis R SouzaInstituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Maria Janieire N N AlvesInstituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0003-3207-623X
Bruna E OnoD'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.ORCID 0000-0003-4235-3691
João E IzaiasD'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
Artur O SalesD'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.ORCID 0000-0001-9795-3745
Thais S RodriguesInstituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Vera M C SalemiInstituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Camila P JordãoInstituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0002-4060-4672
Katia De AngelisDepartment of Physiology, Federal University of São Paulo, São Paulo, Brazil.ORCID 0000-0002-3640-9049
Daniel H CraigheadDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, United States.ORCID 0000-0002-8744-5349
Matthew J RossmanDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, United States.ORCID 0000-0001-9381-2590
Luiz A BortolottoInstituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0002-4865-6442
Fernanda M Consolim-ColomboInstituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0003-3220-019X
Maria C C IrigoyenInstituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0003-2097-3662
Douglas R SealsDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, United States.ORCID 0000-0002-2391-9824
Carlos E NegrãoInstituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Allan R K SalesD'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.ORCID 0000-0002-4407-9043
D’Or Institute for Research and Education · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRUniversity of Colorado Boulder · USUniversidade de São Paulo · BRUniversidade Federal de São Paulo · BR

Funding

Sodium Nitrite Supplementation for Improving Physiological Function in Patients with Chronic Kidney DiseaseK01DK115524 · NIDDK · UNIVERSITY OF COLORADO · PI ROSSMAN, MATTHEW J · 2018 to 2023
$1.1M
Novel time-efficient inspiratory muscle strength training for lowering systolic blood pressure and improving endothelial, cerebrovascular, and cognitive functionK01HL153326 · NHLBI · UNIVERSITY OF MINNESOTA · PI CRAIGHEAD, DANIEL HARRISON · 2020 to 2024
$899k
NHLBI NIH HHS K01 HL153326NIDDK NIH HHS K01 DK115524
6 · The paper itself

Abstract

Previous studies show that COVID-19 survivors have elevated muscle sympathetic nerve activity (MSNA), endothelial dysfunction, and aortic stiffening. However, the neurovascular responses to mental stress and exercise are still unexplored. We hypothesized that COVID-19 survivors, compared with age- and body mass index (BMI)-matched control subjects, exhibit abnormal neurovascular responses to mental stress and physical exercise. Fifteen severe COVID-19 survivors (aged: 49 ± 2 yr, BMI: 30 ± 1 kg/m

Indexed as

COVID-19Hand StrengthAdultBlood PressureExerciseForearmHeart RateHemodynamicsHumansMiddle AgedMuscle, SkeletalSympathetic Nervous Systemexercisemental stressperipheral blood flowsympathetic activityvascular conductance

Identifiers

PMID37449870
PMCPMC10625836
OpenAlexW4384339155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.