Evidence map›Paper›PMID 37449768›Full record

Trial reportPediatric pulmonology2023

Encouraging adherence in adolescents with asthma using financial incentives: An RCT.

Heather H De Keyser, John T Brinton, Samantha Bothwell, Megan Camacho, Allison Kempe, Stanley J Szefler

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Pediatric pulmonology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Heather H De KeyserBreathing Institute, Children's Hospital Colorado, Los Angeles, California, USA.
John T BrintonDepartment of Pediatrics, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, USA.
Samantha BothwellDepartment of Pediatrics, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, USA.
Megan CamachoBreathing Institute, Children's Hospital Colorado, Los Angeles, California, USA.
Allison KempeDepartment of Pediatrics, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, USA.
Stanley J SzeflerBreathing Institute, Children's Hospital Colorado, Los Angeles, California, USA.ORCID 0000-0002-6911-3199
Children's Hospital of Los Angeles · USUniversity of Colorado Anschutz Medical Campus · USChildren's Hospital Colorado · US

Funding

Treatment Phenotypes for Adolescents with AsthmaK23HL146791 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI DE KEYSER, HEATHER · 2020 to 2024
$837k
NHLBI NIH HHS K23 HL146791
6 · The paper itself

Abstract

backgroundMedication adherence in adolescents remains a significant management challenge and innovative strategies are needed to improve medication adherence. Financial incentives have been used to improve outcomes for health behaviors among adults, but have not been well-studied among adolescents. The objective of this study was to test if a modest financial incentive improved medication adherence in adolescents with asthma compared with a control group.

methodsParticipants were randomized to either control (electronic medication monitoring [EMM] with App reminders/feedback for 4 months) or intervention (EMM + $1 per day for perfect medication adherence for 3 months [maximum $84] followed by 1 month of EMM only). A repeated measures mixed model, with a first order autoregressive correlation structure between errors, was used to test the null hypothesis for an interaction of treatment group and week.

resultsFifty-two participants were enrolled, and 48 completed primary analysis. Mean adherence rates declined in both groups over time, and there was no significant difference in the change in adherence rates between the groups (F-statistic = 0.72, ndf = 15, ddf = 625, p = 0.76). Adherence rates (during the 12 weeks when incentives were given) declined from 80% to 64% in the control group, and from 90% to 58% in the incentive group. There was no significant change in the slope of decline in the incentives group in the month following payment discontinuation.

conclusionA modest financial incentive did not lead to significantly different medication adherence rates in adolescents with asthma who were receiving a monitoring and reminder intervention. Further study is needed to determine viable interventions to optimize medication use in this group.

Indexed as

AsthmaMotivationAdolescentAdultHealth BehaviorHumansMedication AdherenceResearch Designadherenceadolescentasthmamotivation

Identifiers

PMID37449768
PMCPMC10538420
OpenAlexW4384339492

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.