Evidence map›Paper›PMID 37449590›Full record

ReviewNeural regeneration research2023

Repair and regeneration of peripheral nerve injuries that ablate branch points.

JuliAnne E Allgood, George D Bittner, Jared S Bushman

Abstract readReview
In one paragraph

Review in Neural regeneration research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. lncRNA ENSRNOT00000087717 mediated differentiation of satellite glial cells derived from dorsal root ganglion via AKT1.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

JuliAnne E AllgoodDivision of Pharmaceutical Sciences, University of Wyoming, Laramie, WY, USA.
George D BittnerDepartment of Neuroscience, The University of Texas at Austin, Austin, TX, USA.
Jared S BushmanDivision of Pharmaceutical Sciences, University of Wyoming, Laramie, WY, USA.

Funding

Wyoming INBRE Phase 4- Equipment Supplement for x-ray diffractometer for Center for Advanced Scientific InstrumentationP20GM103432 · NIGMS · UNIVERSITY OF WYOMING · PI Nicolas A. Blouin · 2012 to 2026
$56.8M
Zebrafish Models of CNS Injury and Locomotor RecoveryP20GM121310 · NIGMS · UNIVERSITY OF WYOMING · PI Qian-Quan Sun · 2017 to 2026
$27.2M
NIGMS NIH HHS P20 GM103432NIGMS NIH HHS P20 GM121310
6 · The paper itself

Abstract

The peripheral nervous system has an extensive branching organization, and peripheral nerve injuries that ablate branch points present a complex challenge for clinical repair. Ablations of linear segments of the PNS have been extensively studied and routinely treated with autografts, acellular nerve allografts, conduits, wraps, and nerve transfers. In contrast, segmental-loss peripheral nerve injuries, in which one or more branch points are ablated so that there are three or more nerve endings, present additional complications that have not been rigorously studied or documented. This review discusses: (1) the branched anatomy of the peripheral nervous system, (2) case reports describing how peripheral nerve injuries with branched ablations have been surgically managed, (3) factors known to influence regeneration through branched nerve structures, (4) techniques and models of branched peripheral nerve injuries in animal models, and (5) conclusions regarding outcome measures and studies needed to improve understanding of regeneration through ablated branched structures of the peripheral nervous system.

Indexed as

allograftanimal modelbranched injuriesfemoral nerveperipheral nerve injuryperipheral nervous systemregenerationrepairsciatic nervesurgical repair

Identifiers

PMID37449590
PMCPMC10358654

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.