Evidence map›Paper›PMID 37449482›Full record

ArticlePsychological medicine2023

Self-harm in pregnancy and the postnatal year: prevalence and risk factors.

Karyn Ayre, Xiaoqin Liu, Louise M Howard, Rina Dutta, Trine Munk-Olsen

Open access · hybridAbstract read
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Article in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Karyn AyreSection of Women's Mental Health, Health Services and Population Research, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.ORCID 0000-0001-9602-4485
Xiaoqin LiuNational Centre for Register-based Research, Aarhus University, Aarhus, Denmark.
Louise M HowardSection of Women's Mental Health, Health Services and Population Research, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.
Rina DuttaSouth London and Maudsley NHS Foundation Trust, Bethlem Royal Hospital, Monks Orchard Road, Beckenham, Kent, London, UK.
Trine Munk-OlsenNational Centre for Register-based Research, Aarhus University, Aarhus, Denmark.
King's College London · GBAarhus University · DKUniversity of Southern Denmark · DK

Funding

Relapse risk after Discontinuation of Antidepressants during Pregnancy (R-DAP study)R01MH122869 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Veerle Bergink · 2020 to 2026
$4.3M
Health FoundationHorizon 2020 891079National Institute for Health ResearchNIMH NIH HHS R01 MH122869
6 · The paper itself

Abstract

backgroundSelf-harm in pregnancy or the year after birth ('perinatal self-harm') is clinically important, yet prevalence rates, temporal trends and risk factors are unclear.

methodsA cohort study of 679 881 mothers (1 172 191 pregnancies) was conducted using Danish population register data-linkage. Hospital treatment for self-harm during pregnancy and the postnatal period (12 months after live delivery) were primary outcomes. Prevalence rates 1997-2015, in women with and without psychiatric history, were calculated. Cox regression was used to identify risk factors.

resultsPrevalence rates of self-harm were, in pregnancy, 32.2 (95% CI 28.9-35.4)/100 000 deliveries and, postnatally, 63.3 (95% CI 58.8-67.9)/100 000 deliveries. Prevalence rates of perinatal self-harm in women without a psychiatric history remained stable but declined among women with a psychiatric history. Risk factors for perinatal self-harm: younger age, non-Danish birth, prior self-harm, psychiatric history and parental psychiatric history. Additional risk factors for postnatal self-harm: multiparity and preterm birth. Of psychiatric conditions, personality disorder was most strongly associated with pregnancy self-harm (aHR 3.15, 95% CI 1.68-5.89); psychosis was most strongly associated with postnatal self-harm (aHR 6.36, 95% CI 4.30-9.41). For psychiatric disorders, aHRs were higher postnatally, particularly for psychotic and mood disorders.

conclusionsPerinatal self-harm is more common in women with pre-existing psychiatric history and declined between 1997 and 2015, although not among women without pre-existing history. Our results suggest it may be a consequence of adversity and psychopathology, so preventative intervention research should consider both social and psychological determinants among women with and without psychiatric history.

Indexed as

Premature BirthSelf-Injurious BehaviorCohort StudiesFemaleHumansInfant, NewbornPregnancyPrevalenceRisk Factorsperinatalpostnatalpregnancyprevalencerisk factorsSelf-harm

Identifiers

PMID37449482
PMCPMC10235666
OpenAlexW4210718565

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.