Evidence map›Paper›PMID 37449308›Full record

ArticleSchizophrenia bulletin2023

Neural Signatures of Predictive Strategies Track Individuals Along the Autism-Schizophrenia Continuum.

Luca Tarasi, Maria Eugenia Martelli, Marta Bortoletto, Giuseppe di Pellegrino, Vincenzo Romei

Open access · greenAbstract read
In one paragraph

Article in Schizophrenia bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 46 citations in OpenAlex.

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  4. Prior Expectations Bias Confidence Judgments Through Parietal Alpha-Band Modulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Luca TarasiDipartimento di Psicologia, Alma Mater Studiorum - Università di Bologna, Centro Studi e Ricerche in Neuroscienze Cognitive, Campus di Cesena, via Rasi e Spinelli, 176, 47521 Cesena, Italy.ORCID 0000-0002-4977-3173
Maria Eugenia MartelliDipartimento di Psicologia, Alma Mater Studiorum - Università di Bologna, Centro Studi e Ricerche in Neuroscienze Cognitive, Campus di Cesena, via Rasi e Spinelli, 176, 47521 Cesena, Italy.
Marta BortolettoLaboratorio di Neurofisiologia, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, via pilastroni, 4, 25125 Brescia, Italy.
Giuseppe di PellegrinoDipartimento di Psicologia, Alma Mater Studiorum - Università di Bologna, Centro Studi e Ricerche in Neuroscienze Cognitive, Campus di Cesena, via Rasi e Spinelli, 176, 47521 Cesena, Italy.ORCID 0000-0001-7080-4758
Vincenzo RomeiDipartimento di Psicologia, Alma Mater Studiorum - Università di Bologna, Centro Studi e Ricerche in Neuroscienze Cognitive, Campus di Cesena, via Rasi e Spinelli, 176, 47521 Cesena, Italy.
University of Bologna · ITCentro San Giovanni di Dio Fatebenefratelli · ITUniversidad Nebrija · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and hypothesisHumans develop a constellation of different representations of the external environment, even in the face of the same sensory exposure. According to the Bayesian framework, these differentiations could be grounded in a different weight assigned to prior knowledge vs. new external inputs in predictive inference. Since recent advances in computational psychiatry suggest that autism (ASD) and schizophrenia (SSD) lie on the two diametric poles of the same predictive continuum, the adoption of a specific inferential style could be routed by dispositional factors related to autistic and schizotypal traits. However, no studies have directly investigated the role of ASD-SSD dimension in shaping the neuro-behavioral markers underlying perceptual inference. STUDY

designWe used a probabilistic detection task while simultaneously recording EEG to investigate whether neurobehavioral signatures related to prior processing were diametrically shaped by ASD and SSD traits in the general population (n = 80).

resultsWe found that the position along the ASD-SSD continuum directed the predictive strategies adopted by the individuals in decision-making. While proximity to the positive schizotypy pole was associated with the adoption of the predictive approach associated to the hyper-weighting of prior knowledge, proximity to ASD pole was related to strategies that favored sensory evidence in decision-making.

conclusionsThese findings revealed that the weight assigned to prior knowledge is a marker of the ASD-SSD continuum, potentially useful for identifying individuals at-risk of developing mental disorders and for understanding the mechanisms contributing to the onset of symptoms observed in ASD and SSD clinical forms.

Indexed as

Autism Spectrum DisorderAutistic DisorderSchizophreniaBayes TheoremHumansPersonalityPhenotypealpha oscillationscomputational psychiatryperceptual decision-makingpredictive coding

Identifiers

PMID37449308
PMCPMC10483460
OpenAlexW4384264200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.