ArticleChemical science2023
Direct mechanocatalysis by resonant acoustic mixing (RAM).
Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 63 citations in OpenAlex.
- Synchrotron X-ray powder diffraction validation of real-time in situ terahertz-Raman monitoring of resonant acoustic mixing cocrystallization.Communications chemistry · 2026Article
- Article
- Mechanochemically Synthesized Amidetriazoles for Effective Optical and Electrochemical Detection of Anions.The Journal of organic chemistry · 2026Article
- Silent Partners in the Mill: Unveiling the Role of Additives in Mechanochemical Synthesis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Review
- Shaking Up Photochemistry: The Future Frontiers of Mechanophotocatalysis.ACS central science · 2026Review
- Energy Distribution during Resonant Acoustic Mixing.ACS omega · 2025Article
- Formation of Racemic Phases of Amino Acids by Liquid-Assisted Resonant Acoustic Mixing Monitored by Solid-State NMR Spectroscopy.Molecules (Basel, Switzerland) · 2025Article
- How to Track Mechanochemical Reactions in Resonant Acoustic Mixers by in Situ Raman Spectroscopy.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Process Integration and Life-Cycle Assessment of Moist-Solid Hydrolysis of Polylactic Acid with Lactic Acid Recovery via Electrodialysis.ChemSusChem · 2025Article
- Solid-State Photochemistry in Resonant Acoustic Mixers.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Multigram-Scale Organic Synthesis by Resonant Acoustic Mixing: Application to the Sustainable Preparation of Active Pharmaceutical Ingredients.ChemSusChem · 2025Article
- From Micro to Marvel: Unleashing the Full Potential of Click Chemistry with Micromachine Integration.Micromachines · 2025Review
- A scalable photo-mechanochemical platform for sustainable photoredox catalysis by resonant acoustic mixing.Nature communications · 2025Article
- Photochemical Stabilization of Self-Assembled Spherical Nucleic Acids.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Rapid and scalable ruthenium catalyzed meta-C-H alkylation enabled by resonant acoustic mixing.Communications chemistry · 2024Article
- Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We demonstrate the use of a metal surface to directly catalyse copper-catalysed alkyne-azide click-coupling (CuAAC) reactions under the conditions of Resonant Acoustic Mixing (RAM) - a recently introduced and scalable mechanochemical methodology that uniquely eliminates the need for bulk solvent, as well as milling media. By using a simple copper coil as a catalyst, this work shows that direct mechanocatalysis can occur in an impact-free environment, relying solely on high-speed mixing of reagents against a metal surface, without the need for specially designed milling containers and media. By introducing an experimental setup that enables real-time Raman spectroscopy monitoring of RAM processes, we demonstrate 0th-order reaction kinetics for several selected CuAAC reactions, supporting surface-based catalysis. The herein presented RAM-based direct mechanocatalysis methodology is simple, enables the effective one-pot, two-step synthesis of triazoles
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.