Evidence map›Paper›PMID 37448891›Full record

ArticleIndian journal of nephrology

Donor-Specific Antibody Detection by Single-Antigen Bead Assay for Renal Transplantation: A 2-Year Experience from South India.

Mamidi Neeraja, Sreedhar Kesireddy, Neerudi Raj Kumar, Madasu Praveen Kumar, Potlapally Pullaiah, Raju Chittampalli

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Indian journal of nephrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Mamidi NeerajaDepartment of Transplant Immunology, Apollo Hospitals, Jubilee Hills, Hyderabad, Telangana, India.
Sreedhar KesireddyDepartment of Transplant Immunology, Apollo Hospitals, Jubilee Hills, Hyderabad, Telangana, India.
Neerudi Raj KumarDepartment of Transplant Immunology, Apollo Hospitals, Jubilee Hills, Hyderabad, Telangana, India.
Madasu Praveen KumarDepartment of Transplant Immunology, Apollo Hospitals, Jubilee Hills, Hyderabad, Telangana, India.
Potlapally PullaiahDepartment of Transplant Immunology, Apollo Hospitals, Jubilee Hills, Hyderabad, Telangana, India.
Raju ChittampalliDepartment of Transplant Immunology, Apollo Hospitals, Jubilee Hills, Hyderabad, Telangana, India.
Creative Commons · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Recipient sensitization against donor human leukocyte antigens (HLA) plays a key role in transplant rejection, and this risk is best minimized by efficient pre transplant antibody detection. Determination of antibody specificity with the highest sensitivity and degree of resolution to the allelic antigen level is achieved by using single-antigen bead (SAB) assay. Methods: This study evaluated the correlation of Luminex cross match (LXM) with SAB assay for detection of donor-specific antibodies (DSA). A total of 2075 renal transplant patients were screened for the presence of DSA by LXM, complement-dependent cytotoxicity (CDC) cross match, and 125 patients for SAB from January 2018 to December 2019. Results: There was a male preponderance among recipients ( Conclusion: In conclusion, LXM, if used in combination with SAB assay and HLA typing of donors if necessary for virtual cross match, will help in avoiding unnecessary exclusion of donors for renal transplant recipients and also for post transplant monitoring of recipients, especially in cadaveric donor transplants.

Indexed as

Donor–Specific Antibodiesluminex Cross matchrenal transplantationSingle antigen bead assay

Identifiers

PMID37448891
PMCPMC10337226
OpenAlexW4380089200

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.