Evidence map›Paper›PMID 37448797›Full record

ArticleFrontiers in medicine2023

Non-invasive estimation of split renal function from routine

Matthias Weissinger, Kyra Celine Seyfried, Stephan Ursprung, Salvador Castaneda-Vega, Ferdinand Seith, Sebastian von Beschwitz, Jonas Vogel, Patrick Ghibes, Konstantin Nikolaou, Christian la Fougère and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Matthias WeissingerDepartment of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Tuebingen, Germany.
Kyra Celine SeyfriedDepartment of Nuclear Medicine and Clinical Molecular Imaging, University Hospital Tuebingen, Tuebingen, Germany.
Stephan UrsprungDepartment of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Tuebingen, Germany.
Salvador Castaneda-VegaDepartment of Nuclear Medicine and Clinical Molecular Imaging, University Hospital Tuebingen, Tuebingen, Germany.
Ferdinand SeithDepartment of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Tuebingen, Germany.
Sebastian von BeschwitzDepartment of Nuclear Medicine and Clinical Molecular Imaging, University Hospital Tuebingen, Tuebingen, Germany.
Jonas VogelDepartment of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Tuebingen, Germany.
Patrick GhibesDepartment of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Tuebingen, Germany.
Konstantin NikolaouDepartment of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Tuebingen, Germany.
Christian la FougèreDepartment of Nuclear Medicine and Clinical Molecular Imaging, University Hospital Tuebingen, Tuebingen, Germany.
Helmut DittmannDepartment of Nuclear Medicine and Clinical Molecular Imaging, University Hospital Tuebingen, Tuebingen, Germany.
University of Tübingen · DEDeutschen Konsortium für Translationale Krebsforschung · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Patients with impaired kidney function are at elevated risk for nephrotoxicity and hematotoxicity from peptide receptor radionuclide therapy (PPRT) for advanced neuroendocrine tumors. Somatostatin receptor (SSR)-PET/CT imaging is the method of choice to identify sufficient SSR expression as a prerequisite for PRRT. Therefore, our study aimed to explore whether split renal function could be evaluated using imaging data from routine SSR-PET/CT prior to PRRT. Methods: In total, 25 consecutive patients who underwent SSR-PET/CT (Siemens Biograph mCT Results: SUVmean of the parenchymal tracer retention showed a negative correlation with TER Conclusion: This pilot study indicates that static [

Indexed as

accumulation indexDOTATATENET (neuro-endocrinal tumors)PRRT (peptide receptor radionuclide therapy)single-sided renal functionsplit renal functionSSR PET/CTtotal kidney accumulation

Identifiers

PMID37448797
PMCPMC10337782
OpenAlexW4382585472

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.