Evidence map›Paper›PMID 37448499›Full record

ArticleJournal of craniovertebral junction & spine

The impact of demineralized bone matrix characteristics on pseudarthrosis and surgical outcomes after posterolateral lumbar decompression and fusion.

Jeremy C Heard, Yunsoo Lee, Mark J Lambrechts, Emily Berthiaume, Nicholas D D'Antonio, John Bodnar, John Paulik, John J Mangan, Jose A Canseco, Mark F Kurd and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of craniovertebral junction & spine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. A Review of Synthetic Bone Grafts in Lumbar Interbody Fusion.Bioengineering (Basel, Switzerland) · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Jeremy C HeardRothman Orthopaedic Institute, Philadelphia, PA, USA.
Yunsoo LeeRothman Orthopaedic Institute, Philadelphia, PA, USA.
Mark J LambrechtsDepartment of Orthopaedic Surgery, Washington University, St. Louis, MO, USA.
Emily BerthiaumeRothman Orthopaedic Institute, Philadelphia, PA, USA.
Nicholas D D'AntonioRothman Orthopaedic Institute, Philadelphia, PA, USA.
John BodnarRothman Orthopaedic Institute, Philadelphia, PA, USA.
John PaulikRothman Orthopaedic Institute, Philadelphia, PA, USA.
John J ManganRothman Orthopaedic Institute, Philadelphia, PA, USA.
Jose A CansecoRothman Orthopaedic Institute, Philadelphia, PA, USA.
Mark F KurdRothman Orthopaedic Institute, Philadelphia, PA, USA.
I David KayeRothman Orthopaedic Institute, Philadelphia, PA, USA.
Alexander R VaccaroRothman Orthopaedic Institute, Philadelphia, PA, USA.
Christopher K KeplerRothman Orthopaedic Institute, Philadelphia, PA, USA.
Gregory D SchroederRothman Orthopaedic Institute, Philadelphia, PA, USA.
Alan S HilibrandRothman Orthopaedic Institute, Philadelphia, PA, USA.
Rothman Orthopaedics · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The objectives of our study were to compare the fusion rates and surgical outcomes of lumbar fusion surgery based on the (1) type of demineralized bone matrix (DBM) carrier allograft, (2) the presence/absence of a carrier, and (3) the presence of bone fibers in DBM. Methods: Patients >18 years of age who underwent single-level posterolateral decompression and fusion (PLDF) between L3 and L5 between 2014 and 2021 were retrospectively identified. We assessed bone grafts based on carrier type (no carrier, sodium hyaluronate carrier, and glycerol carrier) and the presence of bone fibers. Fusion status was determined based on a radiographic assessment of bony bridging, screw loosening, or change in segmental lordosis >5°. Analyses were performed to assess fusion rates and surgical outcomes. Results: Fifty-four patients were given DBM with a hyaluronate carrier, 75 had a glycerol carrier, and 94 patients were given DBM without a carrier. DBM carrier type, bone fibers, and carrier presence had no impact on 90-day readmission rates ( Conclusion: Our study found no significant differences between DBM containing glycerol, sodium hyaluronate, or no carrier regarding fusion rates or surgical outcomes after single-level PLDF. Bone particulates versus bone fibers also had no significant differences regarding the likelihood of bony fusion.

Indexed as

Bone matrixlumbar fusionpseudarthrosissurgical outcomes

Identifiers

PMID37448499
PMCPMC10336891
OpenAlexW4384277468

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.