Evidence map›Paper›PMID 37448486›Full record

ArticleEpilepsy & behavior reports2023

Use of intranasal rescue therapy for seizure clusters in students with epilepsy: Nurses' knowledge, perceptions, and practice.

Nancy Santilli, Sandra Dewar, Cynthia Guerra, Sunita N Misra, Adrian L Rabinowicz, Enrique Carrazana

Open access · goldAbstract read
In one paragraph

Article in Epilepsy & behavior reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Short-Term Impact of Seizures and Mitigation Opportunities.Current neurology and neuroscience reports · 2024
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Nancy SantilliHuman Care Systems, 720-84 State St, Boston, MA 02109, United States.
Sandra DewarDepartment of Neurology, Virginia Commonwealth University School of Medicine, 1101 E Marshall St, Richmond, VA 23298-0599, United States.
Cynthia GuerraNeurelis, Inc., 300-3430 Carmel Mountain Rd, San Diego, CA 92121, United States.
Sunita N MisraNeurelis, Inc., 300-3430 Carmel Mountain Rd, San Diego, CA 92121, United States.
Adrian L RabinowiczNeurelis, Inc., 300-3430 Carmel Mountain Rd, San Diego, CA 92121, United States.
Enrique CarrazanaNeurelis, Inc., 300-3430 Carmel Mountain Rd, San Diego, CA 92121, United States.
Neurelis (United States) · USUniversity of Hawaiʻi at Mānoa · USVirginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

School nurses play a crucial role in the prompt, appropriate response to epilepsy-related seizure emergencies among students in the school setting. Two intranasal benzodiazepine rescue therapies are now approved and offer potential benefits of being easy to use and socially acceptable. In July 2021, a survey was sent to 49,314 US school nurses to assess knowledge, perceptions, and practice with seizure rescue therapy. Responses were received from 866 (1.8% response rate). Of respondents, 45.7% had used rectal diazepam gel; 9.3%, midazolam nasal spray; and 6.0%, diazepam nasal spray. The majority (58.7%) had not delegated authority to administer rescue therapy, with state/local regulations and lack of willingness of school personnel being the most common barriers to delegation (37.7% and 20.1%, respectively). Additional training of nurses and school staff and progress on delegation policies may help optimize appropriate use of intranasal rescue therapy for seizures and enhance care of students with epilepsy in schools.

Indexed as

BenzodiazepineDiazepamEpilepsyIntranasalRescue therapySchool

Identifiers

PMID37448486
PMCPMC10337358
OpenAlexW4367187370

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.