Evidence map›Paper›PMID 37448440›Full record

ArticlePulmonary circulation2023

Partially hydrolyzed guar gum suppresses the progression of pulmonary arterial hypertension in a SU5416/hypoxia rat model.

Takayuki J Sanada, Koji Hosomi, Jonguk Park, Akira Naito, Seiichiro Sakao, Nobuhiro Tanabe, Jun Kunisawa, Koichiro Tatsumi, Takuji Suzuki

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pulmonary circulation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Takayuki J SanadaLaboratory of Vaccine Materials and Laboratory of Gut Environmental System, Microbial Research Center for Health and Medicine, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) National Institutes of Biomedical Innovation, Health, and Nutrition (NIBIOHN) Osaka Japan.ORCID https://orcid.org/0000-0001-5725-1810
Koji HosomiLaboratory of Vaccine Materials and Laboratory of Gut Environmental System, Microbial Research Center for Health and Medicine, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) National Institutes of Biomedical Innovation, Health, and Nutrition (NIBIOHN) Osaka Japan.
Jonguk ParkArtificial Intelligence Center for Health and Biomedical Research National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) Osaka Japan.
Akira NaitoDepartment of Respirology, Graduate School of Medicine Chiba University Chiba Japan.
Seiichiro SakaoDepartment of Respirology, Graduate School of Medicine Chiba University Chiba Japan.
Nobuhiro TanabeDepartment of Respirology, Graduate School of Medicine Chiba University Chiba Japan.
Jun KunisawaLaboratory of Vaccine Materials and Laboratory of Gut Environmental System, Microbial Research Center for Health and Medicine, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) National Institutes of Biomedical Innovation, Health, and Nutrition (NIBIOHN) Osaka Japan.
Koichiro TatsumiDepartment of Respirology, Graduate School of Medicine Chiba University Chiba Japan.
Takuji SuzukiDepartment of Respirology, Graduate School of Medicine Chiba University Chiba Japan.
Chiba University · JPNational Institute of Biomedical Innovation, Health and Nutrition · JPWaseda University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the effects of partially hydrolyzed guar gum (PHGG) on the development of pulmonary arterial hypertension using a SU5416/hypoxia rat model. Our results demonstrated that PHGG treatment suppressed the development of pulmonary hypertension and vascular remodeling with an altered gut microbiota composition.

Indexed as

Akkermansiabacteroidetes S27‐7dietary fibergut dysbiosisprebiotics

Identifiers

PMID37448440
PMCPMC10336776
OpenAlexW4384108592

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.