Evidence map›Paper›PMID 37448403›Full record

ArticleCureus2023

Intestinal Spirochetosis and Chronic Diarrhea: A Case Report and Literature Review.

Samuel D Novick, Mefthe Berhanu, Yordanos G Negassi, Selamawit W Demissie, Syeda Areeba Hussain Kazmi, Shaniah S Holder

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 5 countries.

Samuel D NovickGeneral Surgery, Nassau University Medical Center, East Meadow, USA.
Mefthe BerhanuHealth Science, University of Texas Health Science Center at Houston, Houston, USA.
Yordanos G NegassiInternal Medicine, Learn and Live Wholestic Health Services Clinic, Alexandria, USA.
Selamawit W DemissieInternal Medicine, Global Health Services, Virginia, USA.
Syeda Areeba Hussain KazmiInternal Medicine, Karachi Medical and Dental College, Karachi, PAK.
Shaniah S HolderMedicine, American University of Barbados School of Medicine, Bridgetown, BRB.
American University of BarbadosGlobal Services (Slovakia) · SKKarachi Medical and Dental College · PKLear (United States) · USNassau University Medical Center · USThe University of Texas Health Science Center at Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spirochetosis is a rare condition characterized by the presence of spirochetes in the gastrointestinal tract. It is typically associated with immunodeficiency. We present a case of chronic watery diarrhea in a 48-year-old housewife who had a 12-week history of variable-volume bowel movements without blood or mucus, accompanied by a sense of urgency. Chronic diarrhea led to weight loss and fatigue, significantly impacting her quality of life. Despite the absence of known risk factors, a comprehensive clinical evaluation and exclusion of other potential causes prompted a rectosigmoid biopsy, which revealed distinctive histological findings of spirochetosis. This case underscores the significance of considering spirochetosis as a differential diagnosis in cases of chronic watery diarrhea, even in the absence of immunodeficiency. The utilization of rectosigmoid biopsy and careful histopathological examination played a pivotal role in establishing an accurate diagnosis.

Indexed as

chronic watery diarrheahistopathologynon-immunodeficientrectosigmoid biopsyspirochetosis

Identifiers

PMID37448403
PMCPMC10336368
OpenAlexW4380264056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.