Evidence map›Paper›PMID 37448269›Full record

ArticleProblemy endokrinologii2023

[Acromegaly in the differential diagnosis of hearing loss].

L K Dzeranova, L I Lepeshkina, A S Shutova, M A Perepelova, E A Pigarova, V N Azizyan, P V Akopyan, Е G Przhialkovskaya, G A Melnichenko, N G Mokrysheva

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In one paragraph

Article in Problemy endokrinologii, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

L K DzeranovaEndocrinology Research Centre.
L I LepeshkinaPeoples' Friendship University of Russia.
A S ShutovaEndocrinology Research Centre.
M A PerepelovaEndocrinology Research Centre.
E A PigarovaEndocrinology Research Centre.
V N AzizyanEndocrinology Research Centre.
P V AkopyanEndocrinology Research Centre.
Е G PrzhialkovskayaEndocrinology Research Centre.
G A MelnichenkoEndocrinology Research Centre.
N G MokryshevaEndocrinology Research Centre.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acromegaly is a multifactorial neuroendocrine disease caused by hyperproduction of growth hormone (GH). In more than 95% of cases the reason of acromegaly the GH-secreting pituitary adenoma. In patients with this neuroendocrine disease, a slowly developing complex of symptom can manifest with concomitant pathological conditions, including auditory function disordersDiagnostic difficulties of acromegaly at the ambulatory stage determine the importance of doctor`s awareness in different medical specialties.Here we demonstrate a clinical case of the improvement of the auditory function due to combined surgical and medical treatment of a patient with the pituitary macroadenoma, acromegaly and hearing loss.Anamnesis features: a patient with an active stage of acromegaly and a pituitary macroadenoma measuring 57x35x32 mm with ante-, supra-, infra-, parasellar spread, (Knosp III(D), Knosp IV(S) noted a violation of auditory function. She was consulted by an otolaryngologist, sensorineural hearing loss on the right of the 3rd degree was diagnosed, on the left of the 1st degree. The patient underwent surgical treatment of pituitary adenoma, noted a significant improvement in auditory function in the early postoperative period. Six months later, repeated audiometry was performed, marked regression of hearing damage was noted.The case described by us indicates the reversibility of a rare complication of acromegaly - hearing loss and the importance of an interdisciplinary approach in the management of patients with this pathology.

Indexed as

AcromegalyAdenomaDeafnessGrowth Hormone-Secreting Pituitary AdenomaHearing LossPituitary NeoplasmsDiagnosis, DifferentialFemaleHumans

Identifiers

PMID37448269
PMCPMC10204780

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