Evidence map›Paper›PMID 37448101›Full record

ArticleGut microbes

Viral metagenomics of the gut virome of diarrheal children with Rotavirus A infection.

Siwen Bao, Hao Wang, Wang Li, Haisheng Wu, Chunying Lu, Liang Yong, Qing Zhang, Xiang Lu, Min Zhao, Juan Lu and 7 more

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Siwen BaoClinical Laboratory Center, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, China.
Hao WangDepartment of Clinical Laboratory, The Affiliated Huai'an Hospital of Xuzhou Medical University, Huai'an, China.
Wang LiClinical Laboratory Center, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, China.
Haisheng WuDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, China.
Chunying LuDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, China.
Liang YongDepartment of Clinical Laboratory, The Affiliated Huai'an Hospital of Xuzhou Medical University, Huai'an, China.
Qing ZhangDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, China.
Xiang LuDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, China.
Min ZhaoDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, China.
Juan LuDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, China.
Jia LiuQinghai Institute of Endemic Disease Prevention and Control, Xining, China.
Chukwudozie Kingsley IkechukwuDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, China.
Juan XuClinical Laboratory Center, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, China.
Ping NiClinical Laboratory Center, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, China.
Ying XiongDepartment of Pharmacy, Yancheng Third People's Hospital, Yancheng, China.
Wen ZhangDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, China.
Chenglin ZhouClinical Laboratory Center, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, China.
Jiangsu University · CNNantong University · CNXuzhou Medical College · CNQinghai Institute for Endemic Diease Prevention and Control · CNYancheng Third People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diarrhea is a leading cause of morbidity and mortality in children worldwide and represents a major dysbiosis event. Rotavirus has been recognized as a global leading pathogen of diarrhea. This study is aimed at investigating differences in the gut virome between diarrheal children and healthy controls. In 2018, 76 diarrheal fecal samples and 27 healthy fecal samples in Shanghai and 40 diarrheal fecal samples and 19 healthy fecal samples in Taizhou were collected to investigate the composition of the gut virome. Viral metagenomic analyses revealed that the alpha diversity of the diarrheal virome was not significantly different from that of the healthy virome, and the beta diversity had a significant difference between diarrheal and healthy children. The diarrheal virome was mainly dominated by the families

Indexed as

Gastrointestinal MicrobiomeRotavirusRotavirus InfectionsChildChinaDiarrheaFecesHumansMetagenomicsdiarrheaenteric virusgut viromephageRotavirus AViral metagenomics

Identifiers

PMID37448101
PMCPMC10351451
OpenAlexW4384277101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.