Evidence map›Paper›PMID 37448026›Full record

ArticleSensors (Basel, Switzerland)2023

Enhancement of Refractive Index Sensitivity Using Small Footprint S-Shaped Double-Spiral Resonators for Biosensing.

Anh Igarashi, Maho Abe, Shigeki Kuroiwa, Keishi Ohashi, Hirohito Yamada

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anh IgarashiGraduate School of Engineering, Tohoku University, Sendai 980-8579, Japan.ORCID 0000-0002-9941-0995
Maho AbeResearch Institute of Electrical Communication, Tohoku University, Sendai 980-8577, Japan.
Shigeki KuroiwaR&D Group, KOKOROMI Inc., Shinjuku-ku, Tokyo 169-0051, Japan.
Keishi OhashiR&D Group, KOKOROMI Inc., Shinjuku-ku, Tokyo 169-0051, Japan.
Hirohito YamadaGraduate School of Engineering, Tohoku University, Sendai 980-8579, Japan.

Funding

The Kao Foundation for Arts and Sciences. Not applicableTUMUG Support Project, Tohoku University Not applicable
6 · The paper itself

Abstract

We demonstrate an S-shaped double-spiral microresonator (DSR) for detecting small volumes of analytes, such as liquids or gases, penetrating a microfluidic channel. Optical-ring resonators have been applied as label-free and high-sensitivity biosensors by using an evanescent field for sensing the refractive index of analytes. Enlarging the ring resonator size is a solution for amplifying the interactions between the evanescent field and biomolecules to obtain a higher refractive index sensitivity of the attached analytes. However, it requires a large platform of a hundred square millimeters, and 99% of the cavity area would not involve evanescent field sensing. In this report, we demonstrate the novel design of a Si-based S-shaped double-spiral resonator on a silicon-on-insulator substrate for which the cavity size was 41.6 µm × 88.4 µm. The proposed resonator footprint was reduced by 680 times compared to a microring resonator with the same cavity area. The fabricated resonator exposed more sensitive optical characteristics for refractive index biosensing thanks to the enhanced contact interface by a long cavity length of DSR structures. High quality factors of 1.8 × 10

Indexed as

Biosensing TechniquesRefractometrySiliconSiliconcavity lengthevanescent field sensingrefractive indexring resonator

Identifiers

PMID37448026
PMCPMC10346211

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.