Evidence map›Paper›PMID 37447372›Full record

ArticleNutrients2023

Preliminary Data on Free Use of Fruits and Vegetables Containing Phenylalanine 76-100 mg/100 g of Food in 16 Children with Phenylketonuria: 6 Months Follow-Up.

Alex Pinto, Anne Daly, Júlio César Rocha, Catherine Ashmore, Sharon Evans, Richard Jackson, Mary Hickson, Anita MacDonald

Abstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alex PintoBirmingham Women's and Children's Hospital, Birmingham B4 6NH, UK.
Anne DalyBirmingham Women's and Children's Hospital, Birmingham B4 6NH, UK.ORCID 0000-0003-2579-8699
Júlio César RochaNutrition and Metabolism, NOVA Medical School, Faculdade de Ciências Médicas, NMS, FCM, Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal.ORCID 0000-0002-4977-8345
Catherine AshmoreBirmingham Women's and Children's Hospital, Birmingham B4 6NH, UK.
Sharon EvansBirmingham Women's and Children's Hospital, Birmingham B4 6NH, UK.ORCID 0000-0002-7654-3621
Richard JacksonCancer Research UK Liverpool Cancer Trials Unit, University of Liverpool, Liverpool L69 3GL, UK.
Mary HicksonSchool of Health Professions, Faculty of Health, University of Plymouth, Plymouth PL4 8AA, UK.ORCID 0000-0001-7996-0095
Anita MacDonaldBirmingham Women's and Children's Hospital, Birmingham B4 6NH, UK.

Funding

National Society for Phenylketonuria We received a National Society for Phenylketonuria (NSPKU) grant for £10000 to support the costs of this study.
6 · The paper itself

Abstract

In phenylketonuria (PKU), a previous intervention study assessing the patients ability to tolerate fruits and vegetables containing phenylalanine 76-100 mg/100 g without limit or measurement, found that an extra 50 mg/day phenylalanine, but not 100 mg/day, was tolerated from these fruits and vegetables. In a further 6-month extension study, we examined the effect of the 'free' use of this group of fruits and vegetables on blood phenylalanine control. For 6 months, the patients ate fruits and vegetables containing phenylalanine 76-100 mg/100 g without limit or measurement. Three-day diet diaries and the patients' weights were collected monthly. Blood phenylalanine spots were collected weekly aiming for blood phenylalanine levels <360 μmol/L. Retrospective blood phenylalanine was collected 6 months pre-trial. All 16 patients (69% females) from the intervention study took part in the extension study. Most of the patients (

Indexed as

PhenylketonuriasVegetablesAdolescentChildFemaleFollow-Up StudiesFruitHumansMalePhenylalaninePreliminary DataRetrospective StudiesPhenylalaninefruitsmetabolic controlphenylalaninephenylketonuriavegetables

Identifiers

PMID37447372
PMCPMC10347155

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.