Evidence map›Paper›PMID 37447352›Full record

ArticleNutrients2023

Women in Selected Communities of Punjab, India Have a High Prevalence of Iron, Zinc, Vitamin B12, and Folate Deficiencies: Implications for a Multiply-Fortified Salt Intervention.

Yvonne E Goh, Mari S Manger, Mona Duggal, Reena Das, Shipra Saklani, Surbhi Agarwal, Deepmala Budhija, Manu Jamwal, Bidhi L Singh, Neha Dahiya and 7 more

Abstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yvonne E GohDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of California, San Francisco, CA 94609, USA.
Mari S MangerDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of California, San Francisco, CA 94609, USA.
Mona DuggalPost Graduate Institute of Medical Education & Research, Chandigarh 160012, India.
Reena DasPost Graduate Institute of Medical Education & Research, Chandigarh 160012, India.
Shipra SaklaniPost Graduate Institute of Medical Education & Research, Chandigarh 160012, India.
Surbhi AgarwalPost Graduate Institute of Medical Education & Research, Chandigarh 160012, India.
Deepmala BudhijaPost Graduate Institute of Medical Education & Research, Chandigarh 160012, India.
Manu JamwalPost Graduate Institute of Medical Education & Research, Chandigarh 160012, India.ORCID 0000-0002-6860-3698
Bidhi L SinghPost Graduate Institute of Medical Education & Research, Chandigarh 160012, India.ORCID 0000-0001-6598-9743
Neha DahiyaPost Graduate Institute of Medical Education & Research, Chandigarh 160012, India.
Hanqi LuoRollins School of Public Health, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0001-6253-5818
Julie M LongDepartment of Pediatrics-Section of Nutrition, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Jamie WestcottDepartment of Pediatrics-Section of Nutrition, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Nancy F KrebsInternational Zinc Nutrition Consultative Group, San Francisco, CA 94609, USA.
Rosalind S GibsonDepartment of Human Nutrition, University of Otago, Dunedin 9054, New Zealand.
Kenneth H BrownInternational Zinc Nutrition Consultative Group, San Francisco, CA 94609, USA.
Christine M McDonaldDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of California, San Francisco, CA 94609, USA.ORCID 0000-0003-1231-9003

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary intake and biomarkers of micronutrient status of 100 non-pregnant women of reproductive age (NPWRA) were assessed to determine optimal levels of iron, zinc, vitamin B12, and folic acid to include in multiply-fortified salt (MFS) that will be evaluated in an upcoming trial. Weighed food records were obtained from participants to measure intake of micronutrients and discretionary salt, and to assess adequacy using Indian Nutrient Reference Values (NRVs). Statistical modeling was used to determine optimal fortification levels to reduce inadequate micronutrient intake while limiting intake above the upper limit. Fasting blood samples were obtained to assess iron, zinc, vitamin B12, and folate status. In usual diets, inadequate intake of iron (46%), zinc (95%), vitamin B12 (83%), and folate (36%) was high. Mean intake of discretionary salt was 4.7 g/day. Prevalence estimates of anemia (37%), iron deficiency (67%), zinc deficiency (34%), vitamin B12 insufficiency (37%), and folate insufficiency (70%) were also high. Simulating the addition of optimized MFS to usual diets resulted in percentage point (pp) reductions in inadequate intake by 29 pp for iron, 76 pp for zinc, 81 pp for vitamin B12, and 36 pp for folate. MFS holds potential to reduce the burden of micronutrient deficiencies in this setting.

Indexed as

Folic Acid DeficiencyMalnutritionFemaleFolic AcidFood, FortifiedHumansIronMicronutrientsPrevalenceSodium ChlorideSodium Chloride, DietaryVitamin B 12ZincFolic AcidIronMicronutrientsSodium ChlorideSodium Chloride, DietaryVitamin B 12Zincdietary intakefood fortificationmicronutrient statusmultiply-fortified saltundernutrition

Identifiers

PMID37447352
PMCPMC10346790

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.