Evidence map›Paper›PMID 37447323›Full record

ArticleNutrients2023

The Mutual Interplay between Bone, Glucose and Lipid Metabolism: The Role of Vitamin D and PTH.

Vittoria Carmela Danese, Jessica Pepe, Federica Ferrone, Luciano Colangelo, Viviana De Martino, Luciano Nieddu, Giancarlo Ferrazza, Enrico Panzini, Roberto Pascone, Frank Blocki and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Vittoria Carmela DaneseDepartment of Clinical, Internal Medicine, Cardiovascular and Anesthesiological Sciences, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.
Jessica PepeDepartment of Clinical, Internal Medicine, Cardiovascular and Anesthesiological Sciences, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.
Federica FerroneDepartment of Clinical, Internal Medicine, Cardiovascular and Anesthesiological Sciences, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0003-4070-1437
Luciano ColangeloDepartment of Clinical, Internal Medicine, Cardiovascular and Anesthesiological Sciences, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0002-5835-9310
Viviana De MartinoDepartment of Clinical, Internal Medicine, Cardiovascular and Anesthesiological Sciences, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0002-7034-7718
Luciano NiedduFaculty of Economics, Università degli Studi Internazionali di Roma, Via Cristoforo Colombo 200, 00147 Rome, Italy.ORCID 0000-0001-5174-3347
Giancarlo FerrazzaDepartment of Immunohematology and Transfusion Medicine, Policlinico Umberto I, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.
Enrico PanziniDepartment of Immunohematology and Transfusion Medicine, Policlinico Umberto I, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.
Roberto PasconeDepartment of Pediatrics, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.
Frank BlockiDiaSorin Inc., 1951 Northwestern Avenue, Stillwater, MN 55082, USA.
Salvatore MinisolaDepartment of Clinical, Internal Medicine, Cardiovascular and Anesthesiological Sciences, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0001-6525-0439
Cristiana CiprianiDepartment of Clinical, Internal Medicine, Cardiovascular and Anesthesiological Sciences, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0002-0141-1202
Policlinico Umberto I · ITSapienza University of Rome · ITUniversità degli Studi Internazionali di Roma · IT

Funding

DiaSorin (Ireland) NASapienza University of Rome 2014
6 · The paper itself

Abstract

backgroundWe sought to investigate the mutual interplay between bone, glucose and lipid metabolism in a wide cohort of community-based subjects.

methodsWe studied 1240 blood donors (F/M ratio 1/3.2, mean age 41.9 ± 11.7 SD). Serum ionized (Ca

results25(OH)D negatively correlated with BMI (R = -0.11), PTH (R = -0.16) (

conclusionVitamin D, PTH, glucose and lipid metabolism are mutually influenced. Hypovitaminosis D predisposes toward worsening lipid profiles through the actions of PTH, while serum PTH levels per se associate with higher glucose and LDL-C levels.

Indexed as

GlucoseVitamin D DeficiencyAdultCholesterol, LDLHumansLipid MetabolismMiddle AgedParathyroid HormoneTriglyceridesVitamin DVitaminsCholesterol, LDLGlucoseParathyroid HormoneTriglyceridesVitamin DVitaminscholesterolglucoseHDLLDLlipidPTHtriglyceridesvitamin D

Identifiers

PMID37447323
PMCPMC10347203
OpenAlexW4382982575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.