Evidence map›Paper›PMID 37447248›Full record

Trial reportNutrients2023

Effect of Milk Fat Globule Membrane- and Protein-Containing Snack Product on Physical Performance of Older Women-A Randomized Controlled Trial.

Satu K Jyväkorpi, Riikka T Niskanen, Marianna Markkanen, Karoliina Salminen, Timo Sibakov, Kaity-Marin Lehtonen, Susanna Kunvik, Kaisu H Pitkala, Anu M Turpeinen, Merja H Suominen

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Satu K JyväkorpiUnit of Primary Health Care, Department of General Practice and Primary Health Care, Faculty of Medicine, Helsinki University Central Hospital, University of Helsinki, 00014 Helsinki, Finland.
Riikka T NiskanenUnit of Primary Health Care, Department of General Practice and Primary Health Care, Faculty of Medicine, Helsinki University Central Hospital, University of Helsinki, 00014 Helsinki, Finland.
Marianna MarkkanenDepartment of Food and Nutrition, University of Helsinki, 00014 Helsinki, Finland.
Karoliina SalminenUnit of Primary Health Care, Department of General Practice and Primary Health Care, Faculty of Medicine, Helsinki University Central Hospital, University of Helsinki, 00014 Helsinki, Finland.ORCID 0000-0003-4704-3211
Timo SibakovValio Ltd., R&D, 00370 Helsinki, Finland.
Kaity-Marin LehtonenValio Ltd., R&D, 00370 Helsinki, Finland.
Susanna KunvikFaculty of Health and Welfare, Satakunta University of Applied Sciences, 28101 Pori, Finland.ORCID 0000-0002-9090-098X
Kaisu H PitkalaUnit of Primary Health Care, Department of General Practice and Primary Health Care, Faculty of Medicine, Helsinki University Central Hospital, University of Helsinki, 00014 Helsinki, Finland.
Anu M TurpeinenValio Ltd., R&D, 00370 Helsinki, Finland.
Merja H SuominenUnit of Primary Health Care, Department of General Practice and Primary Health Care, Faculty of Medicine, Helsinki University Central Hospital, University of Helsinki, 00014 Helsinki, Finland.
University of Helsinki · FIValio (Finland) · FISatakunta University of Applied Sciences · FI

Funding

Valio (Finland) N/A
6 · The paper itself

Abstract

introductionSarcopenia is common in people 70+ years of age, and its prevalence increases with further aging. Insufficient energy and protein intake accelerates muscle loss, whereas sufficient protein intake and milk fat globule membrane (MFGM) may suppress age-associated deterioration of muscle mass and strength. Our objective was to test whether a snack product high in MFGM and protein would improve physical performance in older women.

methodsIn this 12-week randomized controlled trial, women ≥ 70 years, with protein intake < 1.2 g/body weight (BW) kg/day (d), were randomized into intervention (n = 51) and control (n = 50) groups. The intervention group received a daily snack product containing ≥ 23 g of milk protein and 3.6-3.9 g of MFGM. Both groups were advised to perform a five-movement exercise routine. The primary outcome was the change in the five-time-sit-to-stand test between the groups. Secondary outcomes included changes in physical performance, cognition, hand grip strength, and health-related quality of life.

resultsThe change in the five-time-sit-to-stand test did not differ between the intervention and the control groups. The change in the total Short Physical Performance Battery score differed significantly, favoring the intervention group (

conclusionsOur results indicate that the combination of MFGM and protein may improve the physical performance-related balance of older women.

Indexed as

Hand StrengthQuality of LifeAgedFemaleGlycolipidsGlycoproteinsHumansLipid DropletsMuscle StrengthPhysical Functional PerformanceSnacksGlycolipidsGlycoproteinsmilk fat globule5-time-chair-stand testbalancemilk fat globule membraneolder womenproteinSPPB

Identifiers

PMID37447248
PMCPMC10343882
OpenAlexW4382403223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.