Evidence map›Paper›PMID 37447245›Full record

Trial reportNutrients2023

Acute Effect of a Saffron Extract (Safr'Inside

Camille Pouchieu, Line Pourtau, Julie Brossaud, David Gaudout, Jean-Benoit Corcuff, Lucile Capuron, Nathalie Castanon, Pierre Philip

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Camille PouchieuActiv'Inside, F-33750 Beychac et Caillau, France.ORCID 0000-0002-7373-4545
Line PourtauActiv'Inside, F-33750 Beychac et Caillau, France.ORCID 0000-0003-3315-2222
Julie BrossaudHormone Laboratory, Nuclear Medicine, CHU Bordeaux, UMR INRA 1286, University Bordeaux, F-33000 Bordeaux, France.
David GaudoutActiv'Inside, F-33750 Beychac et Caillau, France.ORCID 0000-0002-3255-8274
Jean-Benoit CorcuffHormone Laboratory, Nuclear Medicine, CHU Bordeaux, UMR INRA 1286, University Bordeaux, F-33000 Bordeaux, France.
Lucile CapuronINRAE, Nutrition and Integrative Neurobiology (NutriNeuro), Bordeaux University, UMR 1286, F-33000 Bordeaux, France.
Nathalie CastanonINRAE, Nutrition and Integrative Neurobiology (NutriNeuro), Bordeaux University, UMR 1286, F-33000 Bordeaux, France.ORCID 0000-0002-0079-0562
Pierre PhilipPôle Neurosciences Cliniques, Centre Hospitalier Universitaire de Bordeaux, F-33076 Bordeaux, France.
Complexité, Innovation et Activités Motrices et Sportives · FRInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FRUniversité de Bordeaux · FRCentre National de la Recherche Scientifique · FR

Funding

Silver Brain Food project, a program co-financed by the "Future Investment Program" (Pro-gramme d'Investissements d'Avenir PIA3) and managed by the Investment General Secretariat and operated by Bpifrance R209836
6 · The paper itself

Abstract

According to animal studies, saffron and its main volatile compound safranal may reduce biological and behavioral signs of acute stress. However, little is known about its impact in humans. This study investigated the acute effect of a saffron extract and safranal on the biological and psychological stress responses in healthy men experiencing a laboratory stress procedure. In this double-blind, placebo-controlled, randomized, cross-over study, 19 volunteers aged 18-25 received a single dose of 30 mg saffron extract (Safr'Inside

Indexed as

CortisoneCrocusAdolescentAdultAnimalsCross-Over StudiesCyclohexenesDouble-Blind MethodHumansHydrocortisoneMalePlant ExtractsTerpenesYoung AdultCortisoneCyclohexenesHydrocortisonePlant ExtractssafranalTerpenesanxietycorticotropic axissaffron extractsafranalstressterpene

Identifiers

PMID37447245
PMCPMC10346743
OpenAlexW4382402990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.