Evidence map›Paper›PMID 37446899›Full record

ArticleMolecules (Basel, Switzerland)2023

Optimization of the Composition of Mesoporous Polymer-Ceramic Nanocomposite Granules for Bone Regeneration.

Marta Trzaskowska, Vladyslav Vivcharenko, Wojciech Franus, Tomasz Goryczka, Adrian Barylski, Agata Przekora

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Application and prospects of nanomaterials in osteoporosis treatment.International journal of pharmaceutics: X · 2026
    Review
  2. Research Progress of Bone Grafting: A Comprehensive Review.International journal of nanomedicine · 2025
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Marta TrzaskowskaIndependent Unit of Tissue Engineering and Regenerative Medicine, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.ORCID 0000-0001-6360-6702
Vladyslav VivcharenkoIndependent Unit of Tissue Engineering and Regenerative Medicine, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.ORCID 0000-0002-1526-686X
Wojciech FranusDepartment of Construction Materials Engineering and Geoengineering, Lublin University of Technology, Nadbystrzycka 38 D, 20-618 Lublin, Poland.ORCID 0000-0002-4599-3427
Tomasz GoryczkaInstitute of Materials Engineering, University of Silesia in Katowice, 75 Pułku Piechoty 1A, 41-500 Chorzów, Poland.ORCID 0000-0002-6405-2825
Adrian BarylskiInstitute of Materials Engineering, University of Silesia in Katowice, 75 Pułku Piechoty 1A, 41-500 Chorzów, Poland.ORCID 0000-0002-1863-1471
Agata PrzekoraIndependent Unit of Tissue Engineering and Regenerative Medicine, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.ORCID 0000-0002-6076-1309
Medical University of Lublin · PLUniversity of Silesia in Katowice · PLLublin University of Technology · PL

Funding

National Science Center UMO-2021/41/N/NZ7/01633
6 · The paper itself

Abstract

Difficult-to-treat bone damage resulting from metabolic bone diseases, mechanical injuries, or tumor resection requires support in the form of biomaterials. The aim of this research was to optimize the concentration of individual components of polymer-ceramic nanocomposite granules (nanofilled polymer composites) for application in orthopedics and maxillofacial surgery to fill small bone defects and stimulate the regeneration process. Two types of granules were made using nanohydroxyapatite (nanoHA) and chitosan-based matrix (agarose/chitosan or curdlan/chitosan), which served as binder for ceramic nanopowder. Different concentrations of the components (nanoHA and curdlan), foaming agent (sodium bicarbonate-NaHCO

Indexed as

ChitosanNanocompositesAnimalsBiocompatible MaterialsBone RegenerationCeramicsDurapatiteMicePolymersSepharoseSolventsTissue ScaffoldsBiocompatible MaterialsChitosanDurapatitePolymersSepharoseSolventsbioceramicsbiocompatibilitybiomaterialcalcium phosphatescytotoxicitymicrohardnesspolymersporosity

Identifiers

PMID37446899
PMCPMC10343773
OpenAlexW4383551173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.