Evidence map›Paper›PMID 37446890›Full record

ReviewMolecules (Basel, Switzerland)2023

Arylcyanomethylenequinone Oximes: An Overview of Synthesis, Chemical Transformations, and Biological Activity.

Karolina Kula, Roman Nagatsky, Mikołaj Sadowski, Yevheniia Siumka, Oleg M Demchuk

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Anti-inflammatory effects ofFrontiers in pharmacology · 2024
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Karolina KulaDepartment of Organic Chemistry and Technology, Cracow University of Technology, Warszawska 24, 31-155 Krakow, Poland.ORCID 0000-0001-9991-3077
Roman NagatskyDepartment of Organic Chemistry and Technology, Cracow University of Technology, Warszawska 24, 31-155 Krakow, Poland.ORCID 0000-0002-3178-0965
Mikołaj SadowskiDepartment of Organic Chemistry and Technology, Cracow University of Technology, Warszawska 24, 31-155 Krakow, Poland.ORCID 0000-0002-1045-7093
Yevheniia SiumkaInstitute for Advanced Training of Pharmacy Specialists, National University of Pharmacy, 17 Zahysnynykiv Ukrainy sq., 61001 Kharkiv, Ukraine.
Oleg M DemchukFaculty of Medicine, The John Paul II Catholic University of Lublin, Konstantynow 1J, 20-708 Lublin, Poland.ORCID 0000-0002-5571-1593
Cracow University of Technology · PLJohn Paul II Catholic University of Lublin · PLNational University of Pharmacy · UA

Funding

Polish National Science Centre grant number 2019/33/B/NZ7/01608
6 · The paper itself

Abstract

Quinone methides are a class of biologically active compounds that can be used in medicine as antibacterial, antifungal, antiviral, antioxidant, and anti-inflammatory agents. In addition, quinone methides have the potential to be used as pesticides, dyes, and additives for rubber and plastics. In this paper, we discuss a subclass of quinone methides: methylenequinone oximes. Although the first representatives of the subgroup were synthesized in the distant past, they still need to be additionally studied, while their chemistry, biological properties, and perspective of practical applications require to be comprehensively summarised. Based on the analysis of the literature, it can be concluded that methylenequinone oximes exhibit a diversified profile of properties and outstanding potential as new drug candidates and reagents in organic synthesis, both of electrophilic and nucleophilic nature, worthy of wide-ranging further research.

Indexed as

IndolequinonesOximesAnti-Bacterial AgentsAnti-Bacterial AgentsIndolequinonesOximesquinone methidearylcyanomethylenequinone oximesbiological activitychemical transformationquinonequinonemethide

Identifiers

PMID37446890
PMCPMC10343898
OpenAlexW4383376318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.