Evidence map›Paper›PMID 37446848›Full record

ArticleMolecules (Basel, Switzerland)2023

Homogeneous Electrochemical Aptamer Sensor Based on Two-Dimensional Nanocomposite Probe and Nanochannel Modified Electrode for Sensitive Detection of Carcinoembryonic Antigen.

Zhengzheng Yan, Shiyue Zhang, Jiyang Liu, Jun Xing

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Zhengzheng YanGeneral Surgery Department, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan 030032, China.
Shiyue ZhangDepartment of Chemistry, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Jiyang LiuDepartment of Chemistry, Zhejiang Sci-Tech University, Hangzhou 310018, China.ORCID 0000-0003-3699-1646
Jun XingDepartment of Breast Surgery, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan 030032, China.
Shanxi Medical University · CNZhejiang Sci-Tech University · CN

Funding

Shanxi Province 136 Revitalization Medical Project Construction Funds 136Zhejiang Provincial Natural Science Foundation of China LY20B050007
6 · The paper itself

Abstract

A rapid and convenient homogeneous aptamer sensor with high sensitivity is highly desirable for the electrochemical detection of tumor biomarkers. In this work, a homogeneous electrochemical aptamer sensor is demonstrated based on a two-dimensional (2D) nanocomposite probe and nanochannel modified electrode, which can realize sensitive detection of carcinoembryonic antigen (CEA). Using π-π stacking and electrostatic interaction, CEA aptamer (Apt) and cationic redox probe (hexaammineruthenium(III), Ru(NH

Indexed as

Biosensing TechniquesNanocompositesBiomarkers, TumorCarcinoembryonic AntigenElectrochemical TechniquesElectrodesHumansLimit of DetectionBiomarkers, TumorCarcinoembryonic Antigencarcinoembryonic antigenelectrochemical aptamer sensorhomogeneousnanochannel arraytwo-dimensional nanocomposite probe

Identifiers

PMID37446848
PMCPMC10343182
OpenAlexW4382936547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.