Evidence map›Paper›PMID 37446810›Full record

ArticleMolecules (Basel, Switzerland)2023

Design, Synthesis, and Acute Toxicity Assays for Novel Thymoquinone Derivative TQFL12 in Mice and the Mechanism of Resistance to Toxicity.

Ting Li, Qi Tan, Chunli Wei, Hui Zou, Xiaoyan Liu, Zhiqiang Mei, Pengfei Zhang, Jingliang Cheng, Junjiang Fu

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Analysis of Pharmacological Properties ofLife (Basel, Switzerland) · 2025
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ting LiKey Laboratory of Epigenetics and Oncology, The Research Center for Preclinical Medicine, Southwest Medical University, Luzhou 646000, China.
Qi TanKey Laboratory of Epigenetics and Oncology, The Research Center for Preclinical Medicine, Southwest Medical University, Luzhou 646000, China.
Chunli WeiKey Laboratory of Epigenetics and Oncology, The Research Center for Preclinical Medicine, Southwest Medical University, Luzhou 646000, China.
Hui ZouKey Laboratory of Epigenetics and Oncology, The Research Center for Preclinical Medicine, Southwest Medical University, Luzhou 646000, China.
Xiaoyan LiuKey Laboratory of Epigenetics and Oncology, The Research Center for Preclinical Medicine, Southwest Medical University, Luzhou 646000, China.
Zhiqiang MeiKey Laboratory of Epigenetics and Oncology, The Research Center for Preclinical Medicine, Southwest Medical University, Luzhou 646000, China.
Pengfei ZhangNHC Key Laboratory of Cancer Proteomics, Department of Oncology, Central South University, Changsha 410008, China.ORCID 0000-0003-3470-085X
Jingliang ChengKey Laboratory of Epigenetics and Oncology, The Research Center for Preclinical Medicine, Southwest Medical University, Luzhou 646000, China.ORCID 0000-0002-9022-7246
Junjiang FuKey Laboratory of Epigenetics and Oncology, The Research Center for Preclinical Medicine, Southwest Medical University, Luzhou 646000, China.ORCID 0000-0002-0708-2200
Southwest Medical University · CNCentral South University · CNHunan Normal University · CN

Funding

National Natural Science Foundation of China 81672887, 82073263the Foundation of Science and Technology Department of Sichuan Province 2022NSFSC0737the Sichuan Science and Technology Program 2022YFS0623-C3, 2022YFS0623-C4
6 · The paper itself

Abstract

TQFL12 is a novel derivative designed and synthesized on the basis of Thymoquinone (TQ) which is extracted from

Indexed as

LiverSignal TransductionAMP-Activated Protein KinasesAnimalsBenzoquinonesMiceAMP-Activated Protein KinasesBenzoquinonesthymoquinoneAMPKαanti-cancermousetoxicityTQTQFL12triple-negative breast cancer

Identifiers

PMID37446810
PMCPMC10343667
OpenAlexW4382982490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.