Development of a Methodology for Determination of Dioxins and Dioxin-like PCBs in Meconium by Gas Chromatography Coupled to High-Resolution Mass Spectrometry (GC-HRMS).

Iñaki Lacomba, Antonio López, Raquel Hervàs-Ayala, Clara Coscollà

Open access · goldAbstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.2field-weighted citation impact, top 50% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Iñaki LacombaFoundation for the Promotion of Health and Biomedical Research of the Valencian Region, FISABIO-Public Health, Av. Catalunya, 21, 46020 Valencia, Spain.

Antonio LópezFoundation for the Promotion of Health and Biomedical Research of the Valencian Region, FISABIO-Public Health, Av. Catalunya, 21, 46020 Valencia, Spain.

Raquel Hervàs-AyalaDepartment of Obstetrics and Gynaecology, General University Hospital of Valencia, 46014 Valencia, Spain.

Clara CoscollàFoundation for the Promotion of Health and Biomedical Research of the Valencian Region, FISABIO-Public Health, Av. Catalunya, 21, 46020 Valencia, Spain.ORCID 0000-0001-5914-9721

Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana · ESHospital General Universitario De Valencia · ESUniversitat de València · ES

Funding

European Commission ERDF 2014-2020

6 · The paper itself

Abstract

An analytical strategy was applied to investigate polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and dioxin-like polychlorinated biphenyls (dl-PCBs) in newborn meconium samples. The methodology includes extraction by selective pressurized liquid extraction (SPLE), followed by a clean-up multicolumn step. The samples were injected by gas chromatography coupled to a high-resolution mass spectrometer (GC-HRMS). The surrogate recoveries ranged from 68% to 95%, and the average of the limit of quantification (LOQ) ranged from 0.03 to 0.08 pg g

Indexed as

BenzofuransDioxinsPolychlorinated BiphenylsPolychlorinated DibenzodioxinsDibenzofuransGas Chromatography-Mass SpectrometryHumansInfant, NewbornMeconiumBenzofuransDibenzofuransDioxinsPolychlorinated BiphenylsPolychlorinated Dibenzodioxinsdioxinsdl-PCBshigh-resolution mass spectrometryhuman biomonitoringmeconium

Identifiers

PMID37446668

DOI10.3390/molecules28135006

PMCPMC10343527

OpenAlexW4382456664

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.