Evidence map›Paper›PMID 37446618›Full record

ArticleMolecules (Basel, Switzerland)2023

Evaluation of Antimicrobial Activities against Various

Pawel Serafin, Paweł Kowalczyk, Adriano Mollica, Azzurra Stefanucci, Anna K Laskowska, Magdalena Zawadzka, Karol Kramkowski, Patrycja Kleczkowska

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Exploring Nepicastat Activity: Beyond DβH.International journal of molecular sciences · 2025
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Pawel SerafinMilitary Institute of Hygiene and Epidemiology, 01-163 Warsaw, Poland.
Paweł KowalczykDepartment of Animal Nutrition, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, 05-110 Jabłonna, Poland.ORCID 0000-0003-4025-3750
Adriano MollicaDepartment of Pharmacy, University "G. d'Annunzio" of Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy.ORCID 0000-0002-7242-4860
Azzurra StefanucciDepartment of Pharmacy, University "G. d'Annunzio" of Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy.ORCID 0000-0001-7525-2913
Anna K LaskowskaCentre for Preclinical Research and Technology (CePT), Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Medical University of Warsaw, 02-097 Warsaw, Poland.
Magdalena ZawadzkaMilitary Institute of Hygiene and Epidemiology, 01-163 Warsaw, Poland.ORCID 0000-0003-0176-6609
Karol KramkowskiDepartment of Physical Chemistry, Medical University of Bialystok, 15-089 Białystok, Poland.
Patrycja KleczkowskaMilitary Institute of Hygiene and Epidemiology, 01-163 Warsaw, Poland.ORCID 0000-0002-8389-0920
University of Chieti-Pescara · ITWojskowy Instytut Higieny i Epidemiologii · PLKielanowski Institute of Animal Physiology and Nutrition · PLMedical University of Białystok · PLMedical University of Lodz · PLMedical University of Warsaw · PL

Funding

Medical University of Białystok B.SUB.23.359Medical University of Białystok SUB/2/NN/22/001/2201National Science Center 2021/43/B/NZ7/01903
6 · The paper itself

Abstract

Finding the ideal antimicrobial drug with improved efficacy and a safety profile that eliminates antibiotic resistance caused by pathogens remains a difficult task. Indeed, there is an urgent need for innovation in the design and development of a microbial inhibitor. Given that many promising antimicrobial peptides with excellent broad-spectrum antibacterial properties are secreted by some frog species (e.g., bombesins, opioids, temporins, etc.), our goal was to identify the antimicrobial properties of amphibian-derived dermorphin and ranatensin peptides, which were combined to produce a hybrid compound. This new chimera (named LENART01) was tested for its antimicrobial activity against

Indexed as

Anti-Infective AgentsEscherichia coliAnti-Bacterial AgentsLipopolysaccharidesMicrobial Sensitivity TestsAnti-Bacterial AgentsAnti-Infective AgentsLipopolysaccharidesantimicrobial activityE. coli cellshybrid peptideMBCMICopioids

Identifiers

PMID37446618
PMCPMC10343207
OpenAlexW4382133981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.