Evidence map›Paper›PMID 37446559›Full record

ArticleMolecules (Basel, Switzerland)2023

Use of Germination to Enhance Resveratrol Content and Its Anti-Inflammatory Activity in Lipopolysaccharide-Stimulated RAW264.7 Cells.

Chaiwat Monmai, Jin-Suk Kim, So-Hyeon Baek

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chaiwat MonmaiDepartment of Agricultural Life Science, Sunchon National University, Suncheon 59722, Republic of Korea.ORCID 0000-0002-9267-3047
Jin-Suk KimDepartment of Agricultural Life Science, Sunchon National University, Suncheon 59722, Republic of Korea.
So-Hyeon BaekDepartment of Agricultural Life Science, Sunchon National University, Suncheon 59722, Republic of Korea.ORCID 0000-0001-5426-0842
Sunchon National University · KR

Funding

National Research Foundation of Korea 2020R1I1A3071908
6 · The paper itself

Abstract

Inflammation is triggered by a variety of danger signals and is now a worldwide concern. Resveratrol, a natural nonflavonoid polyphenol found in naturally consumed plants and foods, has a wide spectrum of bioactive potency. We successfully generated resveratrol-enriched rice by introducing the resveratrol biosynthesis gene into Dongjin rice. In this study, resveratrol- and piceid-enriched rice (DJ526) was investigated for its anti-inflammatory activity in lipopolysaccharide (LPS)-stimulated RAW264.7 cells compared to normal rice (DJ). In addition, the 5-day-old germinated DJ526 (DJ526_5) was tested for its anti-inflammatory effects. The piceid and resveratrol amounts increased in DJ526_5 by germination. Treatment of LPS-stimulated RAW264.7 cells with resveratrol-enriched rice seed extracts (DJ526_0 and DJ526_5) significantly decreased the production of nitric oxide (NO) and the inflammatory mediator prostaglandin E2 (PGE

Indexed as

LipopolysaccharidesStilbenesAnimalsAnti-Inflammatory AgentsGlucosidesMiceNF-kappa BNitric OxideNitric Oxide Synthase Type IIRAW 264.7 CellsResveratrolAnti-Inflammatory AgentsGlucosidesLipopolysaccharidesNF-kappa BNitric OxideNitric Oxide Synthase Type IIpolydatinResveratrolStilbenesanti-inflammationgerminationmitogen-activated protein kinasenuclear factor kappa Bpiceidresveratroltransgenic rice

Identifiers

PMID37446559
PMCPMC10343481
OpenAlexW4381617962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.