Evidence map›Paper›PMID 37446401›Full record

ArticleInternational journal of molecular sciences2023

Bacterial Outer Membrane Vesicles Loaded with Perhexiline Suppress Tumor Development by Regulating Tumor-Associated Macrophages Repolarization in a Synergistic Way.

Shoujin Jiang, Wei Fu, Sijia Wang, Guanshu Zhu, Jufang Wang, Yi Ma

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. ATheranostics · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Drug design, development and therapy · 2024
    Article
  10. Review
  11. International journal of nanomedicine · 2024
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shoujin JiangSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Wei FuSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Sijia WangSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Guanshu ZhuSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Jufang WangSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.ORCID 0000-0002-9908-1001
Yi MaSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
South China University of Technology · CN

Funding

Guangdong Key Areas R&D Program 2022B1111080007Natural Science Foundation of Guangdong Province 2022A1515010716
6 · The paper itself

Abstract

Tumor-associated macrophages (TAMs) promote tumor development and metastasis and are categorized into M1-like macrophages, suppressing tumor cells, and M2-like macrophages. M2-like macrophages, occupying a major role in TAMs, can be repolarized into anti-tumoral phenotypes. In this study, outer membrane vesicles (OMVs) secreted by

Indexed as

NeoplasmsTumor-Associated MacrophagesBacterial Outer MembraneEscherichia coliHumansMacrophagesPerhexilinePerhexilineimmunomodulatoryM1M2OMVsperhexilinerepolarizationTAMs

Identifiers

PMID37446401
PMCPMC10342243
OpenAlexW4383819995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.