Evidence map›Paper›PMID 37446383›Full record

ArticleInternational journal of molecular sciences2023

Exploring the Pathophysiologic Cascade Leading to Osteoclastogenic Activation in Gaucher Disease Monocytes Generated via CRISPR/Cas9 Technology.

Maximiliano Emanuel Ormazabal, Eleonora Pavan, Emilio Vaena, Dania Ferino, Jessica Biasizzo, Juan Marcos Mucci, Fabrizio Serra, Adriana Cifù, Maurizio Scarpa, Paula Adriana Rozenfeld and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Maximiliano Emanuel OrmazabalRegional Coordinator Centre for Rare Diseases, Academic Hospital of Udine, 33100 Udine, Italy.ORCID 0000-0003-0455-5532
Eleonora PavanRegional Coordinator Centre for Rare Diseases, Academic Hospital of Udine, 33100 Udine, Italy.
Emilio VaenaInstituto de Estudios Inmunológicos y Fisiopatológicos (IIFP), UNLP, CONICET, Asociado CIC PBA, Facultad de Ciencias Exactas, Departamento de Ciencias Biológicas, La Plata 1900, Argentina.
Dania FerinoInstitute of Clinical Pathology, Department of Laboratory Medicine, University Hospital of Udine, 33100 Udine, Italy.
Jessica BiasizzoInstitute of Clinical Pathology, Department of Laboratory Medicine, University Hospital of Udine, 33100 Udine, Italy.
Juan Marcos MucciInstituto de Estudios Inmunológicos y Fisiopatológicos (IIFP), UNLP, CONICET, Asociado CIC PBA, Facultad de Ciencias Exactas, Departamento de Ciencias Biológicas, La Plata 1900, Argentina.
Fabrizio SerraRegional Coordinator Centre for Rare Diseases, Academic Hospital of Udine, 33100 Udine, Italy.
Adriana CifùDipartimento di Area Medica, Università degli Studi di Udine, 33100 Udine, Italy.ORCID 0000-0002-6794-8838
Maurizio ScarpaRegional Coordinator Centre for Rare Diseases, Academic Hospital of Udine, 33100 Udine, Italy.
Paula Adriana RozenfeldInstituto de Estudios Inmunológicos y Fisiopatológicos (IIFP), UNLP, CONICET, Asociado CIC PBA, Facultad de Ciencias Exactas, Departamento de Ciencias Biológicas, La Plata 1900, Argentina.ORCID 0000-0002-8138-3087
Andrea Elena DardisRegional Coordinator Centre for Rare Diseases, Academic Hospital of Udine, 33100 Udine, Italy.ORCID 0000-0001-7024-8181
University of Udine · ITConsejo Nacional de Investigaciones Científicas y Técnicas · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gaucher disease (GD) is caused by biallelic pathogenic variants in the acid β-glucosidase gene (

Indexed as

Gaucher DiseaseCell DifferentiationCRISPR-Cas SystemsHumansMonocytesOsteogenesisboneGaucher diseaseinflammationmonocytesosteoclasts

Identifiers

PMID37446383
PMCPMC10342917
OpenAlexW4383818521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.