Evidence map›Paper›PMID 37446182›Full record

ReviewInternational journal of molecular sciences2023

Manipulating Microbiota in Inflammatory Bowel Disease Treatment: Clinical and Natural Product Interventions Explored.

Mengjie Zhu, Yijie Song, Yu Xu, Hongxi Xu

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Special Issue "Drugs in Inflammatory Bowel Diseases".International journal of molecular sciences · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Antioxidants (Basel, Switzerland) · 2024
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Discovery ofInternational journal of molecular sciences · 2023
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mengjie ZhuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Yijie SongSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.ORCID 0000-0002-3088-3719
Yu XuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.ORCID 0000-0003-4395-0498
Hongxi XuShuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

Funding

the Guangdong Province Key Area R&D Program of China 2020B1111110003the NSFC-Joint Foundation of Yunnan Province U1902213
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a complex multifactorial chronic inflammatory disease, that includes Crohn's disease (CD) and ulcerative colitis (UC), having progressively increasing global incidence. Disturbed intestinal flora has been highlighted as an important feature of IBD and offers promising strategies for IBD remedies. A brief overview of the variations occurring in intestinal flora during IBD is presented, and the role of the gut microbiota in intestinal barrier maintenance, immune and metabolic regulation, and the absorption and supply of nutrients is reviewed. More importantly, we review drug research on gut microbiota in the past ten years, including research on clinical and natural drugs, as well as adjuvant therapies, such as Fecal Microbiota Transplantation and probiotic supplements. We also summarize the interventions and mechanisms of these drugs on gut microbiota.

Indexed as

Colitis, UlcerativeCrohn DiseaseInflammatory Bowel DiseasesMicrobiotaHumansIntestinesgut microbiomeimmunityinflammatory bowel diseasemetabolitesnatural productssynthetic drugs

Identifiers

PMID37446182
PMCPMC10342055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.