Evidence map›Paper›PMID 37446084›Full record

ReviewInternational journal of molecular sciences2023

The Stage-Based Model of Addiction-Using

Pearl N Cummins-Beebee, Maggie M Chvilicek, Adrian Rothenfluh

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Learning & memory (Cold Spring Harbor, N.Y.) · 2024
    Review
  5. Role ofInternational journal of molecular sciences · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Pearl N Cummins-BeebeeDepartment of Psychiatry, University of Utah, Salt Lake City, UT 84112, USA.ORCID 0000-0001-5909-1312
Maggie M ChvilicekDepartment of Psychiatry, University of Utah, Salt Lake City, UT 84112, USA.
Adrian RothenfluhDepartment of Psychiatry, University of Utah, Salt Lake City, UT 84112, USA.ORCID 0000-0002-3813-5723
University of Utah · US

Funding

Control of Alcohol Responses by Actin-Regulating GenesR01AA019526 · NIAAA · UT SOUTHWESTERN MEDICAL CENTER · PI ROTHENFLUH, ADRIAN · 2010 to 2025
$5.4M
Transcriptional Regulation of Alcohol Sensitivity and ToleranceR01AA030881 · NIAAA · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Adrian Rothenfluh · 2023 to 2026
$2.1M
Mechanisms of alcohol-induced plasticitey mediated by Arf6R01AA026818 · NIAAA · UNIVERSITY OF UTAH · PI ROTHENFLUH, ADRIAN · 2018 to 2022
$1.7M
Genetic, molecular, and neural mechanisms of alcohol-induced effects on sleepF31AA030209 · NIAAA · UNIVERSITY OF UTAH · PI CHVILICEK, MARGARET · 2022 to 2024
$113k
NIAAA NIH HHS F31 AA030209NIAAA NIH HHS R01 AA019526NIAAA NIH HHS R01 AA026818NIAAA NIH HHS R01 AA030881
6 · The paper itself

Abstract

Addiction is a progressive and complex disease that encompasses a wide range of disorders and symptoms, including substance use disorder (SUD), for which there are few therapeutic treatments. SUD is the uncontrolled and chronic use of substances despite the negative consequences resulting from this use. The progressive nature of addiction is organized into a testable framework, the neurobiological stage-based model, that includes three behavioral stages: (1) binge/intoxication, (2) withdrawal/negative affect, and (3) preoccupation/anticipation. Human studies offer limited opportunities for mechanistic insights into these; therefore, model organisms, like

Indexed as

Behavior, AddictiveSubstance-Related DisordersAnimalsDrosophilaDrosophila melanogasterEthanolHumansMammalsEthanoladdictionanhedoniaassaysDrosophilasubstance use disorder

Identifiers

PMID37446084
PMCPMC10341944
OpenAlexW4382751032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.